The Mechanism of MicroRNAs Network in Alzheimer's Disease

MicroRNAs network, such as MicRNA107 et al, regulate the pathology of Alzheimer's disease and the clinical validation in diagnosis AD.

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Key information

Conditions

Alzheimer Disease Brain Diseases Central Nervous System Diseases Dementia Mental Disorders Nervous System Diseases Neurocognitive Disorders Neurodegenerative Diseases Tauopathies

Age range

60 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Psychogeriatrics，Shanghai Mental Health Center

Shanghai, Shanghai Municipality, 200030, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

NIA-AA MCI due to AD clinical criteria for MCI due to AD
NIA-AA AD clinical criteria for AD

Exclusion criteria

Other type of dementia

Treatment and study plan

MicRNAs test

Diagnostic Test

plasma micRNAs concentration

Primary outcomes

MicRNAs diagnosis validation for aMCI

Time frame: 5 years

MicRNAs concentration in plasma among three groups

Sponsors and collaborators

Lead sponsor

Shanghai Mental Health Center

Other

Registry information

Official study title

Shanghai Mental Health Center

Acronym: MicroRNAs AD

Important dates

Study start: 2016
Primary completion: 2019
Study completion: 2019
First posted: Sep 24, 2021
Registry last updated: Sep 24, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed