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Recruiting

NCT Number: NCT00707694

The Longevity Genes in Founder Populations Project

We believe extreme longevity is due to specific genes which function to delay aging and prevent disease. The purpose of the research is to identify the genes/mutations associated with healthier aging; to understand the biological functions of these genes/mutations; and to develop therapies to replicate these preservative genetic activities in individuals who do not have the genetic profile for longevity.

Recruiting

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Key information

Conditions

Extreme Longevity

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Private Homes, New York, United States

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ashkenazi Jewish, age 95+,
  • Offspring of person age 95+,
  • Offspring of parents who died age 70 or younger.

Exclusion criteria

  • Non-Ashkenazis

Study contacts

Contact information is provided by the study sponsor or research team.

Tina Gao

CONTACT

[email protected]

718-839-7176

Sponsors and collaborators

Lead sponsor

Albert Einstein College of Medicine

Other

Collaborators

  • American Federation for Aging Research
  • Boston University
  • Columbia University
  • Harvard Medical School (HMS and HSDM)
  • National Institute on Aging (NIA)
  • Regeneron Pharmaceuticals
  • Rutgers Health
  • Stanford University
  • Tufts Medical Center
  • University of Minnesota
  • University of Rochester
  • Weill Medical College of Cornell University

Registry information

Official study title

Searching for Longevity Genes in the Historically Unique Ashkenazi Jewish Population

Important dates

Study start
1998
Primary completion
2032
Study completion
2032
First posted
Jul 1, 2008
Registry last updated
Jan 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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