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NCT Number: NCT05217589

The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

Many athletes anecdotally report modifying their nutritional intake before competition in order to avoid gut problems, but no studies have evaluated whether emotional state impacts tolerance to pre-exercise feeding. Therefore, this study will use movie clips (stressful, horror, and funny/amusing) to induce different mood states and emotions, which will be followed by ingestion of food before endurance running on a treadmill. In addition, metabolic and physiologic responses to mood induction will be evaluated.

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Key information

Conditions

Other Gastrointestinal Disorders Colic Congenital, Hereditary, and Neonatal Diseases and Abnormalities Cramp, Abdominal Infant, Newborn, Diseases

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Human Performance Laboratory

Norfolk, Virginia, 23529, United States

Location status: Recruiting

Location contact

Patrick Wilson

CONTACT

[email protected]

7576834783

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 18 to 55 years
  • Able to run for 30 min at a moderate-to-vigorous intensity without stopping
  • No diagnosis or signs/symptoms of cardiovascular disease (CVD) or metabolic disorders
  • Currently physically active (at least 3 days/week of exercise at a moderate or higher intensity)
  • No visual or hearing impairments interfering with ability to see and hear video clips
  • No allergies to ingredients in Boost drink

Exclusion criteria

  • Aged <18 or >55 years
  • Unable to run for 30 min at a moderate-to-vigorous intensity without stopping
  • A diagnosis or signs/symptoms of CVD or metabolic disorders
  • Currently physically inactive (< 3 days/week of exercise at a moderate or higher intensity)
  • Visual or hearing impairments interfering with ability to see and hear video clips
  • Allergies to ingredients in Boost drink

Treatment and study plan

Funny/Amusing Video Clips

Other

Participants watch 5-7 minutes of video clips that are funny/amusing in nature

Horror/Scary Video Clips

Other

Participants watch 5-7 minutes of video clips that are scary in nature

Thrilling/Suspenseful Video Clips

Other

Participants watch 5-7 minutes of video clips that are thrilling/suspenseful in nature

Primary outcomes

  1. Total exercise gastrointestinal symptom burden

    Time frame: Total GI symptom burden over a 30-minute jogging/running protocol.

    The severity of several gastrointestinal symptoms will be assessed on a validated 0-10 scale. Ratings will be collected every 5 minutes during a 30-minute treadmill jogging/running test. Scores from every 5-minute collection will be summed to calculate total GI symptom scores.

  2. Change in emotion ratings

    Time frame: Change in emotion ratings between immediately pre-video and immediately post-video.

    Anxiety, fear, happiness, amusement, disgust, sadness, and anger on a 0-9 Likert scale. Emotions will be assessed before watching video clips and immediately after watching video clips.

Secondary outcomes

  1. Change over time in exercise heart rate

    Time frame: Heart rate will be measured throughout a 30-minute treadmill jogging/running test. Change over time will be evaluated using mixed ANOVA.

    Heart rate will be measured with a chest-strap (Polar) monitor.

  2. Substrate use

    Time frame: Carbohydrate and fat oxidation rates will be measured during the last 5 min of a 30-minute treadmill jogging/running test.

    Carbohydrate and fat oxidation rates will be estimated from the volumes of oxygen consumption and carbon dioxide production during exercise

  3. Feeling Scale

    Time frame: Ratings on the Feeling Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test.

    The Feeling Scale is a bipolar numerical rating scale ranging from -5 to +5, with descriptors of "very bad" at -5, "neutral" at 0, and "very good" at +5.

  4. Fatigue Scale

    Time frame: Ratings on the Fatigue Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test.

    The Fatigue Scale is Likert-type scale that ranges from 0 (Not Fatigued at All) to 10 (Total Fatigue).

  5. Heart rate post-video

    Time frame: Heart rate will be recorded immediately after videos are viewed.

    Heart rate will be measured with a chest-strap (Polar) monitor.

Study contacts

Contact information is provided by the study sponsor or research team.

Patrick Wilson, PhD

CONTACT

[email protected]

7576834783

Sponsors and collaborators

Lead sponsor

Old Dominion University

Other

Registry information

Important dates

Study start
2022
Primary completion
2025
Study completion
2025
First posted
Feb 1, 2022
Registry last updated
Mar 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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