Istanbul University-Cerrahpasa
Istanbul, 34098, Turkey (Türkiye)
NCT Number: NCT05948436
The rate of heavy blood loss is higher in Cesarean delivery compared to vaginal deliveries. Since postpartum hemorrhage is a life threatening situation to decrease the maternal mortality and morbidity rates, precautions should be taken. In this study, we aim to decrease the amount of postpartum hemorrhage by clamping the uterine artery after the delivery of the baby during Cesarean delivery.
Looking for future studies?
Notify MeFemale
Interventional
Not applicable
Istanbul, 34098, Turkey (Türkiye)
Obstetrical hemorrhage, is the most common cause of maternal mortality and morbidity that could be prevented. It can appear at early and late stage of delivery and after delivery. It Is defined as loss of more than 500 mL of blood in vaginal deliveries, whereas more than 1L of blood during C-section. The rate of heavy blood loss is higher in Cesarean delivery compared to vaginal deliveries. The incidence of postpartum anemia in Europe is 50% while in developing countries like Turkey it rises up to 50-80%. Since postpartum hemorrhage is a life threatening situation to decrease the maternal mortality and morbidity rates, precautions should be taken. To preserve the hemoglobin concentrations and hemostasis and to optimize the patient's results, evidence-based methods should be performed. Given these circumstances, interventions using pharmacological, mechanical and surgical methods are necessary to minimize the blood loss. Uteroronics are the first line treatment options followed by fundal massage, controlled traction of cord and delivery of placenta, bimanual compression, intrauterine hydrostatic balloon. After these interventions, surgical interventions such as compression sutures, bilateral uterine artery ligation, hysterectomy and pelvic tamponade could be performed. In this study, we aim to decrease the amount of preoperative part of postpartum hemorrhage by clamping the uterine artery by Darmklemmen clamp after the delivery of the baby before the delivery of placenta during Cesarean delivery.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
We clamped the uterine artery by Darmklemmen clamp, which grasps the tissue delicately without damage, after the delivery of the baby before the delivery of placenta. The clamp is released after the suturing of Munro-Kerr incision is finished, before bleeding control. The duration of clamping time is recorded.
Time frame: during C-section
by measuring the suction canister
Time frame: during C-section
by weighting the gauze+abdominal compress+under pads used during C-section after subtracting the tare
Time frame: 24 hours
by comparing the preoperative and postoperative hemoglobin and hematocrit values
Time frame: during C-section
minutes
Time frame: postoperative 48 hours
need for relaparatomy, vascular or organ injury
Time frame: during C-section
APGAR scores
Istanbul University - Cerrahpasa
Other
The Impact of Mechanical Methods on the Postpartum Haemorrhage Prophylaxis During Caesarean Section; A Randomized-Controlled Trial
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06192836
Cesarean Section Complications, Dystocia
Ankara, Turkey (Türkiye)
View Trial DetailsNCT04833556
Anesthesia Complication, Blood Transfusion Complication
Bangkok, Thailand
View Trial DetailsNCT06431204
Cesarean Section Complications, Female Urogenital Diseases and Pregnancy Complications
Bangkok, Thailand
View Trial DetailsNCT06970483
Cesarean Section Complications, Delivery Complication
Ankara, Turkey (Türkiye)
View Trial Details