Faculty of Medicine Siriraj Hospital
Bangkok, 10700, Thailand
NCT Number: NCT06431204
The objective of this study is to examine the predictive capability of the Obstetric comorbidity index in the identification of severe maternal morbidity associated with postpartum hemorrhage in patients undergoing cesarean delivery.
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Observational
Bangkok, 10700, Thailand
The prospectively predictive maternal morbidity is imperative to enhance maternal outcomes. There has been development of the obstetric comorbidity index (OBCMI) by Bateman et al. in 2013 and performed with superior performance characteristics relative to general comorbidity measures in an obstetric population. The score has been a growing recognition of the necessity for specialized risk assessment tools tailored specifically to obstetric populations that differ from other populations. For instance, both the Charlson/Romano comorbidity index or the Elixhauser comorbidity score and their adaptations are deficient in accounting for obstetric conditions, thereby limiting their ability to predict obstetric morbidity or mortality.
The Obstetric Comorbidity Index has undergone thorough examination and validation across multiple nations. These findings collectively demonstrate the index's capacity for moderate to high predictive accuracy in anticipating maternal morbidities, accompanied by a commendable discriminative performance.
However, within the context of Thailand, investigations concerning the Obstetric Comorbidity Index and its association with perioperative complications or morbidities in postpartum hemorrhage patients undergoing cesarean delivery remain unexplored. Therefore, this study aims to elucidate the correlation between the Obstetric Comorbidity Index and severe maternal morbidity, while also scrutinizing the prevalence of comorbidities during the perioperative period among patients undergoing cesarean delivery at the largest University hospital, in THAILAND. Predicting the rate of maternal morbidity would be advantageous for facilitating preparation and augmenting awareness of complications during the perioperative period.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
The patients underwent cesarean delivery with the diagnosis of postpartum hemorrhage (ICD-10 coding O72.1)
Exclusion criteria
Obstetric comorbidity index score
Time frame: in 72 hours after cesarean delivery
The prediction of severe maternal morbidity using obstetric comorbidity index presented in C-statistic (AUC of ROC)
Time frame: in 72 hours after cesarean delivery
Perioperative red blood cells transfusion in units
Time frame: in 24 hours after cesarean delivery
Quantity of postpartum hemorrhage in ml.
Time frame: in 24 hours after cesarean delivery
Main cause of postpartum hemorrhage
Time frame: in 24 hours after cesarean delivery
Rate of intensive care unit admission
Time frame: in 72 hours after cesarean delivery
Post operative complications eg. congestive heart failure, TRALI, acute kidney injury
Time frame: at 1-minute and 5-minute after delivery
Neonatal Apgar score from 0 - 10
Time frame: in 72 hours after cesarean delivery
Maternal death rate
Mahidol University
Other
Obstetric Comorbidity Index for Prediction of Perioperative Severe Maternal Morbidity in Patients Undergoing Cesarean Delivery With Postpartum Hemorrhage
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