The Immune System and Psychiatric Disorders

The study is based on a hypothesis that there is interaction between the activity in the immune system and in the mind. To study this, the investigators register different measures for activity in the immune system on patients unselectedly admitted to an acute psychiatric ward. The psychiatric statuses and diagnoses of these patients are carefully defined as well.

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Key information

Conditions

Stress Disorders, Traumatic Bipolar Disorder Bipolar and Related Disorders Depressive Disorder Mental Disorders Mood Disorders Personality Disorders Psychotic Disorders Schizophrenia Schizophrenia Spectrum and Other Psychotic Disorders Trauma and Stressor Related Disorders

Sex eligibility

All sexes

Study type

Observational

Primary location

St Olavs Hospital, Department of Psychiatry, Østmarka Hospital

Trondheim, Middle Norway, N-7040, Norway

About this study

Our hypotheses are first that activity in the immune system influences the psychiatric status in general, second that changes in activity in psychiatric status affect activity in the immune system and third that there are connections between certain psychiatric conditions/disorders and certain features of the immune system.

All patients admitted to a psychiatric acute ward covering an area with a population of 130.000 and with around 1000 admittances to an acute psychiatric ward a year (some readmittances) are asked to participate in the study. Patients fill in a question form regarding psychiatric as well as somatic health with emphasis on diseases involving immune activity. When possible also slight information on the family is registered. Both at the time of admittance and after recovery clinical laboratory tests on somatic status are registered. In addition the level of different cytokines is measured. The psychiatric state and precise diagnoses are registered during the stay. The data will be analysed to uncover connections between psychiatric stress in general as well as specific psychiatric diagnoses and activity in the immune system.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Admission to the adult acute psychiatric ward of a certain geographical area during the study period

Exclusion criteria

Patients that do not agree to participate in the study

Treatment and study plan

Primary outcomes

cytokines

Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Norwegian University of Science and Technology

Other

Collaborators

St. Olavs Hospital

Registry information

Important dates

Study start: 2005
Primary completion: 2008
Study completion: 2008
First posted: Sep 16, 2005
Registry last updated: Mar 13, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed