The Fate of Aortic Valve After SAS Surgery in Children

Aortic valve regurgitation (AR) is a common complication following surgery for subaortic stenosis (SAS), yet the long-term outcomes and risk factors for postoperative significant AR (SAR) remain poorly understood. This study aims to investigate the incidence and risk factors of SAR in SAS patients and evaluate the long-term postoperative outcomes.

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Key information

Conditions

Subaortic Stenosis Aortic Regurgitation Aortic Stenosis, Subvalvular Aortic Valve Disease Aortic Valve Insufficiency Aortic Valve Stenosis Cardiovascular Abnormalities Cardiovascular Diseases Congenital Abnormalities Congenital Heart Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities Heart Defects, Congenital Heart Diseases Heart Valve Diseases Ventricular Outflow Obstruction

Age range

0 year–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Fuwai Hospital

Beijing, Beijing Municipality, 100069, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age from 0-18
Clinical diagnosis of subaortic stenosis and underwent surgery

Exclusion criteria

Diagnosed with hypertrophic cardiomyopathy
Underwent concomitant previous surgical repair for aortic valve or SAS
Follow-up time less than 1 year or lack of detailed information.

Treatment and study plan

Primary outcomes

Rate of Postoperative significant AR (SAR)

Time frame: Through study completion, an average of 4 year

Sponsors and collaborators

Lead sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital

Other

Registry information

Official study title

Aortic Valve Regurgitation After Surgical Repair for Subaortic Stenosis in Children

Important dates

Study start: 2008
Primary completion: 2024
Study completion: 2024
First posted: Dec 27, 2024
Registry last updated: Dec 27, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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