Skip to main content
OpenTrials
Completed

NCT Number: NCT03037125

The Evaluation Of Bone Width Gain Following Split Crest Technique With Or Without Platelet Rich Fibrin( PRF)

Split crest technique is a technique for horizontal bone augmentation used in case of narrow alveolar ridges as an alternative to the more aggressive techniques such as onlay bone grafting, guided bone regeneration (GBR) and distraction osteogenesis

The study goal is to evaluate whether if there will be any benefit of using platelet rich fibrin (PRF) with the split crest technique regarding bone width gain and healing response in comparison with split crest technique alone, where PRF is considered an autologous, growth factor containing material which is easy to collect and is of low cost.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Ridge Deficiency

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of oral and dental medicine, Cairo university

Cairo, 4240310, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with at least one missing tooth in the maxillary region
  • All the selected patients have a bucco-palatal width of the edentulous alveolar ridge from 3.5-5.5mm.
  • All the selected patients have at least 12 mm residual bone height at the edentulous area
  • The recipient site of the implant should be free from any pathological conditions.
  • No diagnosed bone disease or medication known to affect bone metabolism.
  • Patients who are cooperative, motivated, and hygiene conscious.

Exclusion criteria

  • Patients unable to undergo minor oral surgical procedures.
  • Patients with a history of drug abuse or catabolic drugs.
  • Patients with a history of psychiatric disorder.
  • Patients with unrealistic expectations about the esthetic outcome of implant therapy.
  • Patients with insufficient vertical inter-arch space, upon centric occlusion, to accommodate the available restorative components.
  • Patients in the growth stage with partially erupted teeth.
  • Patients who have any systemic condition that may contraindicate implant therapy.
  • Patients who have any habits that might jeopardize the osseointegration process, such as smoking and alcoholism.
  • Patients with parafunctional habits that produce overload on the implant, such as bruxism and clenching.

Treatment and study plan

Split Crest with PRF

Procedure

Narrow ridges are split to increase the ridge width and immediate implants are placed with PRF closing the gap

Split Crest without PRF

Procedure

Narrow ridges are split to increase the ridge width and immediate implants are placed without grafting

Primary outcomes

  1. Bone width gain

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

The Evaluation Of Bone Width Gain Following Split Crest Technique With Or Without PRF In Conjunction With Simultaneous Implant Placement In Narrow Alveolar Ridges: A Randomized Controlled Clinical Trial

Important dates

Study start
2017
Primary completion
2019
Study completion
2019
First posted
Jan 31, 2017
Registry last updated
May 28, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.