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Completed

NCT Number: NCT02959528

The Effects of Working Memory Training in Children With Attention-Deficit/Hyperactivity Disorder

Previous studies indicated that children with attention-deficit/hyperactivity disorder (ADHD) often suffer from deficits in executive function, such as attentional control, inhibition, and working memory. One of these executive functions, working memory, plays a critical role in academic performance and classroom behavior. Working memory is essential for performing complex cognitive tasks such as comprehension, learning, and reasoning. Several studies have shown that training of working memory has positive effects for ADHD and other cognitive disorder in children. However, transfer effects across studies appear to be variable and inconsistent. Event-related potentials can be a useful tool to gain insights into such mechanism. Therefore, the aim of the present study is to investigate both near and far transfer effects of N-back training in children with ADHD. In addition, the recording and analysis of event-related potentials will be adopted while children with ADHD perform the complex visuo-spatial and phonological working memory tasks.

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Key information

Conditions

Attention Deficit Disorder With Hyperactivity Attention Deficit and Disruptive Behavior Disorders Mental Disorders Neurodevelopmental Disorders Psychophysiology

Age range

8 year–10 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chang Gung University

Taoyuan City, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ADHD diagnosed according to criteria specified in Diagnostic and statistical manual of mental disorders (DSM-5)
  • aged between 8 and 10 years
  • intelligence quotient > 80 (based on Test of Nonverbal Intelligence-Third Edition)
  • had normal or corrected-to-normal vision
  • right-handed

Exclusion criteria

  • diagnosis of clinically significant oppositional defiant disorder, Autistic Spectrum Disorders, Asperger's syndrome or depression
  • history of seizures

Treatment and study plan

Working Memory Training

Other

n-back training program

perceptual training

Other

visual-perceptual training program

Primary outcomes

  1. Automated Working Memory Assessment

    Time frame: 6 weeks

    Visuospatial working memory change after intervention measured by Automated Working Memory Assessment

Secondary outcomes

  1. Working memory index in Wechsler Intelligence Scale for Children-IV

    Time frame: 6 weeks

    Verbal working memory change after intervention measured by Working memory index in WISC-IV

  2. Event-related potentials

    Time frame: 6 weeks

    Event-related potentials are measured brain response on effects of working memory training

Sponsors and collaborators

Lead sponsor

Chang Gung Memorial Hospital

Other

Registry information

Important dates

Study start
2015
Primary completion
2016
Study completion
2017
First posted
Nov 9, 2016
Registry last updated
Oct 26, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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