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Completed

NCT Number: NCT03546270

The Effects of Swimming on Elderly Women With Stage-2 Hypertension

Aging is associated with progressive decreases in arterial health and function as well as overall fitness. It is crucial to prevent or reduce the negative effects of aging on the vasculature and fitness components by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a swimming (SWM) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx), muscle strength and aerobic capacity in elderly women with stage 2 hypertension.

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Key information

Conditions

Menopause Cardiovascular Diseases Hypertension Vascular Diseases

Age range

65 year–85 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

Using a parallel experimental design, participants were randomly assigned to either SWM (n=52) or non-exercising control group (n=48) for 20 weeks. Participant in the SWM group trained 3-4 days/week, progressing in duration from 25 to 45 min. Participants' carotid to radial PWV (crPWV), systolic and diastolic BP, AIx, strength and VO2max were measured at baseline and after 20 weeks of their assigned intervention.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • systolic/diastolic BP: 140-179 over 90-119 mm Hg
  • had experienced the absence of menstruation for at least 1 year
  • body mass index <30 kg/m2
  • <1 h of regular exercise per week in the previous year

Exclusion criteria

  • Smoker
  • Taking any medications or hormone therapy in previous year

Treatment and study plan

Swimming

Behavioral

This group completed 20-weeks of swimming

Primary outcomes

  1. Arterial Stiffness

    Time frame: 20-weeks

    via Pulse Wave Velocity

Secondary outcomes

  1. Systolic Blood Pressure

    Time frame: 20-weeks

    systolic blood pressure

  2. Pressure Wave Reflection

    Time frame: 20-weeks

    via Augmentation Index

  3. Muscular Strength

    Time frame: 20-weeks

    via Hand Grip Dynamometer

  4. Cardiorespiratory Endurance (Volume of Maximal Oxygen Consumption)

    Time frame: 20-weeks

    via Cornell Modified Bruce treadmill volume of oxygen consumption maximum (VO2max) test

  5. Diastolic Blood Pressure

    Time frame: 20 weeks

Sponsors and collaborators

Lead sponsor

Pusan National University

Other

Collaborators

  • Dong-Eui University
  • Marymount University
  • University of Nebraska

Registry information

Official study title

The Effects of Swimming Training on Arterial Function, Strength and Cardiorespiratory Capacity in Elderly Women With Stage 2 Hypertension

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jun 6, 2018
Registry last updated
Nov 18, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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