"The Effects of Oxytocin on Patients With Borderline Personality Disorder"

RCT. Two substudies (clinical and experimental). Main objective of the trial is to examine if oxytocin, compared to placebo shows any additional effect on the therapy achievements (outcome) of patients with borderline personality disorder, who receive an in-patient standard psychotherapy (Dialectical-behavioral-therapy, Marsha Linehan (2006)).

Secondary objectives :

Investigate if oxytocin compared to placebo enhances social trust and emotion recognition in patients with borderline personality disorder. Comparison of the effects of Oxytocin on patients with BPD and major depression.

Completed

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Key information

Conditions

Effects of Oxytocin on Borderline Personality Disorder Borderline Personality Disorder Mental Disorders Personality Disorders

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Albert-Ludwigs-Universität-Freiburg

Freiburg im Breisgau, Baden-Würtemberg, 79104, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Gender: Both, male and female
Minimum Age: 18 Years
Maximum Age: 50 Years
Borderline personality disorder or major depression (clinical control group)
Mini Mental Status Test > 27 (capacity to consent)

Exclusion criteria

chronic or acute somatic health problems
Schizophrenia
Bipolar affective disorder
pregnancy
breast feeding
neurological disorder
allergy to antidegradants

Treatment and study plan

Oxytocin

Drug

Oxytocin

Placebo

Other

placebo

Primary outcomes

BPD Symptoms

Time frame: BPD Symptoms

Sponsors and collaborators

Lead sponsor

Prof. Dr. Markus Heinrichs

Other

Registry information

Important dates

Study start: 2011
Primary completion: 2021
Study completion: 2022
First posted: Nov 18, 2010
Registry last updated: Nov 3, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed