The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain. We hypothesize that thin individuals are resistant to weight gain because they respond to periods of overfeeding by increasing fat oxidation, reducing food intake, and increasing physical activity relative to those who gain weight over time.

Completed

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Key information

Conditions

Obesity Behavior Behavior, Animal Body Weight Body Weight Changes Feeding Behavior Motor Activity Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms Thinness Weight Gain

Age range

25 year–35 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Colorado Health Sciences Center

Denver, Colorado, 80262, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Half of the subjects will be women, half will be men,
age 25-35,
a range of BMI's from 19-27, for the 'thin subjects' there should be no 1st degree relatives with a BMI>30.
Subjects should not engage in planned physical activity more than 3 hrs per week.
For the obesity prone group there should be at least 1 1st degree relative with a BMI>30.

Sponsors and collaborators

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Nih

Registry information

Important dates

Study start: 2003
Study completion: 2008
First posted: Nov 14, 2003
Registry last updated: Jan 18, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed