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NCT Number: NCT03116490

The Effects of Anesthesia Type on the Prognosis of Hip Fracture Surgery on Elderly Patients

The aim of this study is to figure out whether anesthesia type have an influence on the prognosis of hip fracture surgery.30-day mortality and morbidity after the surgery are our main observational index,and according to literature and our experience,regional anesthesia may have a better prognosis after hip fracture surgery compared with general anesthesia.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

Hip fracture is a common disease among elderly people,and has a high mortality and morbidity.But,seldom practice can be done to improve this condition.For a long time,whether anesthesia type could influence the prognosis after surgery is controversial.Several studies have confirmed regional anesthesia may be better for patients for its fewer complications.But most studies are retrospective,and information may be less convincing .Besides,as a matter of fact,patients of different anesthesia type may have different status,so,a scoring system may be need for comparing the status of patients of different groups.

Our study is a prospective observational trial.Patients needing hip fracture surgery are divided into two groups according to the anesthesia type during surgery:Regional Anesthesia group(RA),General Anesthesia group(GA).To evaluate the status of patients before surgery,we use Orthopedic POSSUM scoring system.It consists of 12 physiological factors and 6 operative severity factors.Then,we will observe outcome of the two groups and record every complication after surgery.Finally,the initial and adjusted morbidity and mortality according to Orthopedic POSSUM scoring system of the two groups are compared.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with hip fracture;
  • Need surgery;
  • Anesthesia type is regional anesthesia or general anesthesia;
  • Age≥60 years.

Exclusion criteria

  • Choosing conservative treatment;
  • Other types of anesthesia or without anesthesia.

Treatment and study plan

Anesthesia Type

Procedure

RA group uses regional anesthesia(epidural, spinal, combined spinal and epidural anesthesia or nerve block) ,and GA group uses general anesthesia(general anesthesia combined with peripheral nerve blockade, general anesthesia combined with spinal/epidural anesthesia or single general anesthesia) .

Primary outcomes

  1. Mortality

    Time frame: 30-day after surgery

Secondary outcomes

  1. Morbidity

    Time frame: 30-day after surgery

  2. VAS pain score

    Time frame: everyday after surgery,record for 7 days

Other outcomes

  1. The Orthopedic POSSUM score

    Time frame: baseline

Study contacts

Contact information is provided by the study sponsor or research team.

Ting Li, M.D.

CONTACT

[email protected]

00447570150148

Yahe Ge, Medical Student

CONTACT

[email protected]

008615330056542

Sponsors and collaborators

Lead sponsor

Wenzhou Medical University

Other

Registry information

Official study title

The Comparative Effects of Regional or General Anesthesia on the Prognosis of Hip Fracture Surgery on Elderly Patients

Important dates

Study start
2026
Primary completion
2026
Study completion
2028
First posted
Apr 17, 2017
Registry last updated
Jul 24, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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