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Completed

NCT Number: NCT03534427

The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls

The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in prehypertensive adolescent girls. Forty prehypertensive adolescent girls participated in this study. The girls were randomly divided into the jump rope exercise intervention group (EX, n=20) and control group (CON, n=20). The EX group performed a jump rope training program at 40-70% of their heart rate reserve (HRR) 5 days/week for 12 weeks (sessions 50 minutes in duration). The CON group did not participate in any structured or unstructured exercise protocol. Blood pressure, arterial stiffness, plasma nitrate/nitrite levels, endothelin-1, C-reactive protein, and body composition were measured before and after the 12-weeks study.

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Key information

Conditions

Prehypertension Abdominal Obesity Adiposity Behavior Blood Pressure Body Weight Cardiovascular Diseases Motor Activity Nutrition Disorders Nutritional and Metabolic Diseases Obesity Obesity, Abdominal Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms Vascular Diseases

Age range

14 year–16 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • prehypertensive
  • sedentary (no regular exercise training or physical activity within the last year)
  • no weight loss diet during the last six months

Exclusion criteria

  • pregnancy
  • chronic disease
  • daily medication use (including antioxidants and weight loss supplements)

Treatment and study plan

Jump rope exercise intervention

Other

12-week jump rope exercise program

Primary outcomes

  1. Arterial Stiffness

    Time frame: 12 weeks

    Arterial stiffness was measured as measurement of brachial to ankle pulse-wave velocity. This indicates peripheral arterial stiffness, as it measures how quickly a pulse wave propagates from one point to another.

  2. Endothelin-1

    Time frame: 12 weeks

    Levels of Endothelin-1 in blood were measured by Endothelin-1 enzyme immunoassay kit.

  3. Body Mass

    Time frame: 12 weeks

    Body mass was measured to nearest 0.1 kg.

  4. Height

    Time frame: 12 weeks

    Height was measured to nearest 1 cm.

  5. Waist Circumference

    Time frame: 12 weeks

    Waist circumference was measured at midpoint between the lower rib and the iliac crest at the end of a normal expiration using a tape measure.

  6. Body Fat

    Time frame: 12 weeks

    Percent body fat (%) was determined using a bioelectrical impedance-meter.

  7. Lean Body Mass

    Time frame: 12 weeks

    Lean body mass (kg) was determined using a bioelectrical impedance-meter.

  8. Nitrate/Nitrite Levels

    Time frame: 12 weeks

    Nitrate and nitrite levels were assayed using a Griess assay kit.

  9. C-reactive Protein

    Time frame: 12 weeks

    C-reactive protein was assessed using an enzyme immunoassay assay kit

  10. Systolic Blood Pressure

    Time frame: 12 weeks

    Blood pressure was measured in duplicate using an automated sphygmomanometer. The average of the two was recorded as the resting blood pressure.

  11. Diastolic Blood Pressure

    Time frame: 12 weeks

Sponsors and collaborators

Lead sponsor

Pusan National University

Other

Registry information

Official study title

The Effects of a 12-Week Jump Rope Exercise Training Program on Arterial Stiffness, Vasodilating and Vasoconstricting Factors, Inflammatory Markers, and Body Composition in Prehypertensive Adolescent Girls

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
May 23, 2018
Registry last updated
Oct 29, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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