ReNEW Clinic Cohort Study

This is an ongoing, prospective cohort study of children and young adults who are evaluated in the Reversing the Negative Effects of Weight on the Heart (ReNEW) Clinic at Johns Hopkins University.

Demographic and clinical data of patients who agree to participate are obtained via chart review and entered into a longitudinal clinic registry.

Completed

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Key information

Conditions

Hypertension Body Weight Cardiomegaly Cardiovascular Diseases Elevated Blood Pressure Heart Diseases Hypertrophy Hypertrophy, Left Ventricular Left Ventricular Hypertrophy Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Prehypertension Signs and Symptoms Vascular Diseases

Age range

Up to 22 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Johns Hopkins University

Baltimore, Maryland, 21287, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Children and young adults with overweight or obesity referred for evaluation of elevated blood pressure in the ReNEW Clinic at Johns Hopkins University are eligible.

Exclusion criteria

Children who are wards of the state or who are non-English speaking without an in-person interpreter accompanying them to the clinic visit.

Treatment and study plan

Primary outcomes

Demographic and clinical data obtained via chart review

Time frame: 20 years

This is a clinic based registry of cardiovascular disease risk data from participants to be collected over time.

Sponsors and collaborators

Lead sponsor

Johns Hopkins University

Other

Collaborators

National Institutes of Health (NIH)

Registry information

Official study title

Reversing the Negative Cardiovascular Effects of Weight (ReNEW) Clinic Cohort Study

Acronym: ReNEW

Important dates

Study start: 2015
Primary completion: 2026
Study completion: 2026
First posted: Jan 25, 2019
Registry last updated: Jan 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed