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NCT Number: NCT07025668

The Effectiveness of Different Exercise Approaches in Biceps Brachii Long Head Tendinopathy

This study was planned to analyze the changes in tendon cross-sectional area and shoulder pain with different exercise approaches applied in biceps brachii long head tendinopathy.

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Key information

Conditions

Sports Physical Therapy Arthralgia Joint Diseases Muscular Diseases Musculoskeletal Diseases Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Shoulder Pain Signs and Symptoms Tendinopathy Tendon Injuries Wounds and Injuries

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hacettepe University Faculty of Physical Therapy and Rehabilitation

Ankara, Turkey (Türkiye)

Location status: Recruiting

Location contact

Ebru G SEZİK, Msc

CONTACT

[email protected]

05532025875

About this study

There are different conservative treatment options for biceps brachii long head tendinopathy. However, the exercise approaches that can be applied for biceps brachii tendinopathy are not clear in the literature. This study aims to investigate the effectiveness of exercises that include 12 weeks of eccentric training or combined exercise approaches.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Having shoulder pain lasting 3 months or more
  • Without a history of surgery, having a diagnosis of shoulder rotator cuff tendinopathy, rotator cuff stage 1-2 tear or subacromial impingement, and having been diagnosed with secondary biceps long head tendinopathy by a physician
  • Pain level during activity > 3 according to the visual analog scale
  • Patients who have been informed about the study and have given written consent to participate in the study will be included in the study.

Exclusion criteria

  • Acute shoulder injury
  • History of shoulder and cervical surgery
  • Limitation of passive range of motion
  • History of local corticosteroid injection within the last 12 months
  • Patients who cannot comply with the exercise program will be excluded from the study.

Treatment and study plan

Eccentric exercise

Other

In the eccentric exercise group, in addition to strengthening exercises for the periscapular muscles and stretching exercises for the biceps brachii muscle, eccentric strengthening exercises for the biceps brachii muscle will be given. Participants will do the exercises in the groups they were randomized to every day for 12 weeks. They will be called to the clinic once a week for exercise checks.

Combined exercise

Other

In the combined exercise group, in addition to strengthening exercises for the periscapular muscles and stretching exercises for the biceps brachii muscle, progressive isometric, isotonic and plyometric strengthening training will be given to the biceps brachii muscle. Participants will do the exercises in the groups they were randomized to every day for 12 weeks. They will be called to the clinic once a week for exercise checks.

Control Group Exercise

Other

In the control group, strengthening exercises for the periscapular muscles and stretching exercises for the biceps brachii muscle will be given. Strengthening exercises for the biceps brachii muscle will not be given in this group. Participants will do the exercises in the groups they were randomized to every day for 12 weeks. They will be called to the clinic once a week for exercise checks.

Primary outcomes

  1. Tendon Cross-Sectional Area

    Time frame: Baseline and 12 weeks

    Ultrasound will be used to measure tendon cross-sectional area.

Secondary outcomes

  1. Visual Analog Scale (VAS)

    Time frame: Baseline and 12 weeks

    The patient will be asked to mark the severity of his/her pain at rest, at night, and during general activity on a 10 cm line without numbers, and the point they mark will be measured in millimeters with a ruler. The left end of the line indicates no pain, corresponding to 0 cm, while the pain level increases towards the right end of the line, which is marked at 10 cm.

Study contacts

Contact information is provided by the study sponsor or research team.

Ebru G SEZİK, Msc

CONTACT

[email protected]

05532025875

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

Effects of Different Exercise Approaches on Tendon Cross-sectional Area and Pain in Biceps Brachii Long Head Tendinopathy

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 17, 2025
Registry last updated
Jun 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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