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NCT Number: NCT06881173

The Effectiveness of Bu Zhong Yi Qi Tang in Patients with Myasthenia Gravis

Research Background: According to the Myasthenia Gravis Foundation of America (MGFA, 2015), the estimated prevalence of myasthenia gravis is 14-20 per 100,000 people, with a higher prevalence in young female individuals compared to males. However, as individuals age, especially after the age of 50, the prevalence in males becomes higher than in females. myasthenia gravis patients often experience varying degrees of disability, leading to the need for long-term medical care, medication, and lifestyle adjustments. This also gives rise to subsequent challenges in caregiving, affecting both the patients' families and society.

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Key information

Conditions

Myasthenia Gravis Autoimmune Diseases Autoimmune Diseases of the Nervous System Immune System Diseases Neoplasms Neoplasms by Site Nervous System Diseases Nervous System Neoplasms Neurodegenerative Diseases Neuromuscular Diseases Neuromuscular Junction Diseases Paraneoplastic Syndromes Paraneoplastic Syndromes, Nervous System

Age range

20 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

:This study aims to assess the effectiveness of using a combination of traditional Chinese and Western medicine,to improve the meridian energy and autonomic nervous system function of myasthenia gravis patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with ocular myasthenia by a doctor
  • Western medicine prescriptions only take oral Mestinon (Pyrido stigmine Bromide)
  • Patients over 20 years old
  • Can understand and understand Those who can speak Mandarin or Taiwanese
  • those with a clear state of consciousness and no diagnosis of mental illness
  • patients and their families who are willing to receive precise integrated treatment of traditional Chinese and Western medicine.

Exclusion criteria

  • Patients with liver failure or kidney failure
  • Allergy symptoms to traditional Chinese medicine, such as skin itching and redness
  • Patients with malignant tumors
  • Patients currently undergoing radiotherapy and chemotherapy
  • Pregnant
  • Cardiac rhythm device implementer

Treatment and study plan

Bu Zhong Yi Qi Tang

Drug

The experimental group took 15g of Buzhong Yiqi Decoction concentrated powder, 3 times a day, 1 packet each time.

Other names: TE202208013

caramel dyed starch placebo

Drug

The control group took 15 grams of caramel dyed starch placebo, 1 pack at a time, 3 times a day.

Other names: starch placebo

Primary outcomes

  1. meridian energy

    Time frame: 12 weeks

    After taking Buzhong Yiqi Decoction, the energy of the meridians can be balanced. Use a meridian measuring instrument to measure the meridians of the whole body and improve the energy of the meridians to the range of 40-60.

  2. autonomic nervous system function

    Time frame: 12 weeks

    After taking Buzhong Yiqi Decoction, it can change the autonomic nervous system (ANS), reduce the sympathetic nerve energy, increase the parasympathetic nerve energy, and set the standard value of the autonomic nervous system activity between 40-60

Study contacts

Contact information is provided by the study sponsor or research team.

yuting Cheng

CONTACT

[email protected]

+8860988773890

Sponsors and collaborators

Lead sponsor

Cheng, yu-ting

Other

Registry information

Official study title

Efficacy of Meridian Energy and Heart Rate Variability in Patients with Ocular Myasthenia Gravis by Using Chinese and Western Medicine Treatment

Important dates

Study start
2022
Primary completion
2025
Study completion
2025
First posted
Mar 18, 2025
Registry last updated
Mar 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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