Skip to main content
OpenTrials
Completed

NCT Number: NCT07587398

The Effectiveness of Acupuncture on Headaches in Women Undergoing IVF Egg Stimulation

To test the effect of acupuncture in treating headaches, as well as co-measures of stress and emotional distress, in participants during the hormonal stimulation phase prior to an oocyte retrieval. Subjects were identified females at birth experiencing a headache while undergoing a hormone stimulation cycle as part of in vitro fertilization or oocyte cryopreservation. Intervention was an individualized acupuncture treatment with needle retention for thirty minutes. Main outcome measured were headache intensity, level of stress, level of emotional distress.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Headache Emotional Distress Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms Stress (Psychology)

Age range

29 year–49 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Southern California Reproductive Center

Beverly Hills, California, 90210, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult biological female
  • participating in an active hormone stimulation cycle
  • receiving acupuncture treatment for fertility support at SCRC in Beverly Hills with the second investigator
  • experiencing a headache

Exclusion criteria

  • participants undergoing a medicated IUI

Treatment and study plan

Acupuncture

Procedure

Acupuncture treatment with 30 minute needle retention

Primary outcomes

  1. Headache Intensity

    Time frame: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)

    Level of headache intensity scored on a scale of 0-10

Secondary outcomes

  1. Stress

    Time frame: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)

    Level of stress reported by the participant scored on a scale of 0-10 with 0 being defined as "no stress" and 10 being defined as "the highest possible stress"

  2. Emotional Distress

    Time frame: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)

    Level of emotional distress reported by the participant scored on a scale of 0-10 with 0 being defined as "no stress" and 10 being defined as "the highest possible stress"

Sponsors and collaborators

Lead sponsor

Yo San University of Traditional Chinese Medicine

Other

Registry information

Official study title

The Effectiveness of Acupuncture on Headaches in Women Undergoing IVF Egg Stimulation: A Pilot Pre-Post Observational Study

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
May 14, 2026
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.