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Completed

NCT Number: NCT07032935

The Effect of Virtual Reality Glasses on Vital Signs and State Anxiety in Patients Undergoing Coronary Angiography

Virtual reality (VR) glasses are an effective non-pharmacological method for reducing anxiety, supported by a high level of evidence and associated with no known side effects. Techniques involving relaxation and distraction, such as VR, function by suppressing the sympathetic branch of the autonomic nervous system and activating the parasympathetic branch, thereby eliciting a relaxation response.

VR glasses divert the patient's attention away from pain and anxiety. By reducing the sense of unfamiliarity in clinical environments, VR helps patients adapt more easily, leading to enhanced relaxation. This state of relaxation not only alleviates anxiety but also induces favorable physiological responses. These include reductions in blood pressure (BP), heart rate (HR), and respiratory rate (RR), along with an increase in peripheral oxygen saturation (SpO₂). Additionally, the psychological benefits of VR contribute to the reduction of anxiety, stress, fear, and worry.

VR is considered a cost-effective, safe, and non-pharmacological intervention. Several studies support its efficacy. For example, in a study comparing the effects of video games played through VR headsets and iPads on preoperative anxiety in adult patients undergoing sternotomy, anxiety was measured using the Depression Anxiety Stress Scale (DASS), and lower anxiety levels were observed in the VR group. Another study demonstrated that watching nature scenes through VR glasses for five minutes prior to maxillofacial surgery significantly reduced anxiety. Furthermore, research comparing progressive muscle relaxation exercises and VR during arthroscopic knee surgery-measured using the State Anxiety Inventory-indicated that both non-pharmacological interventions were effective in reducing anxiety.

However, despite this growing body of evidence, no study to date has examined the effects of VR applications on anxiety in patients undergoing coronary angiography or pacemaker implantation. This study aims to fill that gap by investigating the comparative effectiveness of virtual reality applications in reducing anxiety in patients undergoing coronary angiography.

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kutahya Health Sciences University

Merkez, Kütahya, 43200, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who will undergo coronary angiography or pacemaker implantation, Not to receive sedation during the procedure, Written and verbal acceptance to participate in the study,

  • Are over 18 years of age,
  • Do not have any psychiatric illness,
  • Do not have any vision, hearing or perception problems,
  • Are at least a primary school graduate,
  • Do not have any disorder/disease affecting decision-making ability (dementia, psychological disorder, etc.)
  • Volunteer to participate in the study,
  • Are open to communication and cooperation.

Exclusion criteria

  • Patients who receive sedation, patients who cannot communicate, patients with visual or hearing impairments, and individuals who do not agree to participate in the research will be included.

Treatment and study plan

Virtual Reality Glasses will be used DURING CORONARY ANGIOGRAPHY APPLICATION

Behavioral

Virtual Reality Glasses will be used DURING CORONARY ANGIOGRAPHY APPLICATION

Primary outcomes

  1. Change in State Anxiety Score

    Time frame: Before the intervention (15 minutes before the procedure), and within the first 15 minutes after the intervention is completed

    Before and after the intervention (pre- and post-intervention) It will be measured using the State Anxiety Inventory (STAI-I). The score varies between 20 and 80.

Secondary outcomes

  1. Change in Vital Signs (Heart Rate)

    Time frame: Before the intervention (15 minutes before the procedure), and within the first 15 minutes after the intervention is completed

    To be measured before and after the virtual reality intervention

  2. Change in Vital Signs (Blood Pressure)

    Time frame: Before the intervention (15 minutes before the procedure), and within the first 15 minutes after the intervention is completed

    To be measured before and after the virtual reality intervention

  3. Change in Vital Signs (Respiratory Rate)

    Time frame: Before the intervention (15 minutes before the procedure), and within the first 15 minutes after the intervention is completed

    To be measured before and after the virtual reality intervention

Sponsors and collaborators

Lead sponsor

Kutahya Health Sciences University

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 24, 2025
Registry last updated
Sep 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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