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OpenTrials
Completed

NCT Number: NCT07474441

Early Coronary Angiography in Advanced Chronic Kidney Disease With Acute Coronary Syndrome

This is the retrospective study regarding the association of invasive coronary angiography and time to renal replacement therapy initiation and mortality in patients with chronic kidney disease stage 4-5 who develop acute coronary syndrome.

Completed

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Key information

Conditions

CKD ACS (Acute Coronary Syndrome) Acute Coronary Syndrome Cardiovascular Diseases Coronary Angiography (CAG) Heart Diseases Myocardial Ischemia Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

About this study

Electronic medical records of adult patients admitted with ACS, by the recorded diagnosis code, between 1 January 2017 and 31 December 2021 at King Chulalongkorn Memorial Hospital, Thailand, were retrospectively reviewed. Eligible patients should have concurrent advanced stage CKD, defined as an eGFR less than 30 mL/min/1.73 m² calculated by the 2021 CKD-EPI creatinine equation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Advanced stage CKD, defined as an eGFR less than 30 mL/min/1.73 m²
  • Diagnosis with ACS, by the recorded diagnosis code, between 1 January 2017 and 31 December 2021 at King Chulalongkorn Memorial Hospital

Exclusion criteria

  • Received maintenance dialysis or kidney transplantation before admission
  • Cardiogenic shock or cardiac arrest
  • Prior PCI or CABG within 12 months
  • Recently diagnosed with ACS within 2 months
  • Had a limited life expectancy due to non-cardiovascular disease
  • Pregnant.

Treatment and study plan

Coronary Angiography

Procedure

Standard coronary angiography

Other names: medication

Primary outcomes

  1. Renal replacement therapy initiation

    Time frame: Until 31 December 2021

    Renal replacement therapy initiation

Secondary outcomes

  1. All-cause mortality

    Time frame: Until 31 Dec 2021

    All-cause mortality

Sponsors and collaborators

Lead sponsor

Chulalongkorn University

Other

Registry information

Official study title

Early Coronary Angiography Associates With Survival Benefit and Longer Time to Initiation of Renal Replacement Therapy in Patients With Advanced Chronic Kidney Disease and Acute Coronary Syndrome: A Survival Analysis

Acronym: CAG in CKD-ACS

Important dates

Study start
2017
Primary completion
2021
Study completion
2021
First posted
Mar 16, 2026
Registry last updated
Mar 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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