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OpenTrials
Completed

NCT Number: NCT01152047

The Effect of Oxytocin on Gastric Emptying

The investigators have seen that oxytocin lowers satiety in healthy subjects. Patients with dyspepsia suffers from decreased accommodation and increased satiety postprandially. The investigators now want to examine whether oxytocin may diminish symptoms in these patients.

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Key information

Conditions

Dyspepsia Lack of Satiety Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Skåne University Hospital

Malmö, 205 02, Sweden

About this study

Patients will come twice for a slow satiety drinking test. Once they will get saline infusion and once oxytocin 40 mU/min. At the same time they register satiety on a VAS scale.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Dyspepsia

Exclusion criteria

  • Age > 65 years
  • Cardiac disease

Treatment and study plan

Oxytocin

Drug

40mU/min as infusion of oxytocin

Other names: syntocinon

Primary outcomes

  1. Satiety

    Time frame: 2 h

    The investigator want to examine whether oxytocin leads to lower satiety scores after intake of the same volume of nutrient

Other outcomes

  1. To see if oxytocin lowers satiety

    Time frame: 2h

    To perform a drinking satiety test twice. Once with oxytocin and once with saline. Then examine whether oxytocin decreases satiety compared to saline

Sponsors and collaborators

Lead sponsor

Skane University Hospital

Other

Registry information

Official study title

The Effect of Oxytocin on Satiety in Patients With Dyspepsia

Important dates

Study start
2010
Primary completion
2015
Study completion
2015
First posted
Jun 29, 2010
Registry last updated
Apr 7, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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