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OpenTrials
Completed

NCT Number: NCT01850511

The Effect of Nasal Hair on Nasal Obstruction

Nasal obstruction is a common complaint prompting presentation to an otolaryngologist. Many studies have been performed quantifying and describing the impact of a number of factors on symptoms of nasal obstruction, including anatomical, neoplastic, infectious, and inflammatory causes. Despite this scrutiny, no attention has been paid to the nasal vibrissae as a potential anatomical contributor to nasal obstruction. The proposed study intends to elucidate that contribution, if any exists.

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Key information

Conditions

Nasal Obstruction Airway Obstruction Nose Diseases Otorhinolaryngologic Diseases Respiration Disorders Respiratory Insufficiency Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Presence of nasal vibrissae
  • Able to tolerate rhinomanometry

Exclusion criteria

  • Anatomical or other obvious cause of obstruction
  • Claustrophobia with rhinomanometry mask

Treatment and study plan

Vibrissae trimming

Procedure

Patients will have oxymetazoline administered prior to assessment of outcome measures to ensure minimal impact of erectile mucosal tissue on measurement.

Application of oxymetazoline

Drug

Afrin will be administered to minimize the impact of erectile mucosal tissue on obstruction.

Other names: Afrin

Primary outcomes

  1. Nasal airflow/pressure

    Time frame: Participants will undergo assessment over a 30 minute period, no follow-up

    Objective measures include airflow and pressure as assessed by Rhinomanometry.

  2. Subjective Nasal Obstruction

    Time frame: Participants will undergo assessment over a 30 minute period, no follow-up

    Subjective measures will be assessed via the modified version of the NOSE outcome instrument-a validated test of subjective nasal obstruction

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

The Effect of Vibrissae on Subjective and Objective Measures of Nasal Obstruction

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
May 9, 2013
Registry last updated
Apr 22, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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