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OpenTrials
Completed

NCT Number: NCT07140250

Using ChatGPT to Help Guide Treatment for Sinus and Nasal Problems

The goal of this clinical trial is to evaluate whether ChatGPT can improve shared decision-making by increasing treatment-related knowledge and reducing decisional conflict in adult patients with chronic rhinosinusitis (CRS) or nasal obstruction who have been deemed candidates for surgery.

The main questions it aims to answer are:

* Does ChatGPT improve patient understanding of CRS/nasal obstruction treatment options compared to widely utilized web searches? * Does ChatGPT reduce decisional conflict regarding surgical versus medical management compared to traditional search engine? Researchers will compare a group using Google (standard internet search with AI turned off) after standard counseling to a group using ChatGPT after standard counseling to see if ChatGPT leads to higher knowledge scores, lower decisional conflict scores, and higher satisfaction with the information platform.

Participants will:

* Complete baseline surveys assessing demographics, treatment-related knowledge, and decisional conflict * Be randomized to use either Google or ChatGPT to research their surgery for 10 minutes after standard in-office counseling * Complete follow-up surveys assessing knowledge, decisional conflict, and satisfaction with the information source * Allow the research team to review their medical record for relevant clinical history and disease-specific quality-of-life scores (SNOT-22)

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UC San Diego

La Jolla, California, 92037, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult (18 years or older) UC San Diego Health System Rhinology patients
  • Diagnosis of chronic rhinosinusitis and/or nasal obstruction based on clinical criteria or radiologic evidence
  • Planning to pursue surgical intervention for CRS or nasal obstruction
  • Ability to complete online survey in English or Spanish

Exclusion criteria

  • Unable to complete survey assessments online via REDCap
  • Under the age of 18 years
  • Vulnerable patient populations such as those who are pregnant and institutionalized individuals
  • Patients with benign and malignant tumors

Treatment and study plan

Education with AI Technology

Other

Shared decision making (SDM) about sinusitis treatment will be facilitated by AI technology via ChatGPT

Education using Traditional Internet Search Engines

Other

Participant Education in Sinusitis using Traditional Internet Search Engines through Google

Primary outcomes

  1. Decisional Conflict Scale (DCS) score

    Time frame: Immediate - Following completion of education using AI vs traditional education

    Change in Decisional Conflict Scale (DCS) score

Secondary outcomes

  1. System usability scale (SUS) scores

    Time frame: Immediate following education

  2. Score on treatment-related knowledge questionnaire (MCQ)

    Time frame: Immediate following education

Sponsors and collaborators

Lead sponsor

Carol Yan

Other

Registry information

Official study title

Shared Decision-Making With ChatGPT for Patients With Sinusitis and Nasal Obstruction

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 24, 2025
Registry last updated
Aug 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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