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OpenTrials
Completed

NCT Number: NCT06140394

The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups

the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients

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Key information

Conditions

Periodontal Inflammation

Age range

60 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Al-Azhar University, Cairo, Nasrcity Nasr Street, Egypt

Loading trial locations.

About this study

2 ml of unstimulated saliva will be collected using spitting method, the collected samples will then be analyzed using Elisa technique for salivary Inducible nitrous oxide synthase levels.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • males and females
  • aged below 40 or above 60
  • periodontitis stage 2
  • no tooth loss due to periodontitis

Exclusion criteria

  • smoking habits
  • history of antibiotics
  • history of systemic diseases

Treatment and study plan

Diode laser

Other

low level diode therapy

non surgical scaling

Other

non surgical scaling using ultrasonic

Primary outcomes

  1. clinical parameters (gingival index)

    Time frame: 6 months

    measurement if the gingival index using scoring system. A score from 0.1-1.0 = mild inflammation; 1.1-2.0 = moderate inflammation from, and 2.1-3.0 signifies severe inflammation.

  2. clinical parameters (clinical attachment loss)

    Time frame: 6 months

    measurement of clinical parameters clinical attachment loss in millimeters

Secondary outcomes

  1. assessment of inducible nitrous oxide synthase levels

    Time frame: 3 months

    measurement of inducible nitrous oxide synthase levels in different age groups before the procedure and after using Elisa kit.

Sponsors and collaborators

Lead sponsor

Faculty of Dental Medicine for Girls

Other Gov

Registry information

Official study title

The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients (A Randomized Clinical Trial)

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Nov 20, 2023
Registry last updated
Jun 28, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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