The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery

The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision). We hypothesize that the fibrin is caused by a low-level infection and could be prevented by the antibiotic.

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Key information

Conditions

Cataract Endophthalmitis Eye Diseases Eye Infections Infections Lens Diseases

Age range

6 month–15 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Presbyterian Church East Africa Kikuyu Hospital

Kikuyu, 00902, Kenya

About this study

The study investigates whether using an antibiotic (cefuroxime) in the anterior chamber of the eye at the end of surgery for cataract in children will reduce the amount of fibrin formation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

bilateral congenital or developmental pediatric cataract

Exclusion criteria

traumatic cataract

Treatment and study plan

cefuroxime

Drug

intracameral cefuroxime 0.1 ml

Other names: Zinacef

Saline placebo

Drug

0.1 ml of Ringers lactate

Other names: Saline

Primary outcomes

Fibrin formation in anterior chamber

Time frame: 4th postoperative day

Sponsors and collaborators

Lead sponsor

Presbyterian Church East Africa Kikuyu Hospital

Other

Registry information

Important dates

Study start: 2008
Primary completion: 2008
Study completion: 2008
First posted: Aug 8, 2008
Registry last updated: Aug 8, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed