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Completed

NCT Number: NCT06549933

The Effect of Cryostimulation on Inflammation and Motor Functions. The Study Was Conducted to Determine the Effect of Five Days of Whole-body Cryostimulation (PBC) on Reducing Inflammation and Improving Motor Skills in Soccer Players

The aim of the study was to determine the effect of a 5-day PBC on reducing inflammation and improving motor skills in soccer players during the initial phase of the training period.

The five-day cryostimulation applied did not significantly affect the profile of inflammatory markers in soccer players. However, a reduction in visuo-motor reaction time (RT) was registered in PBC-treated soccer players, suggesting the potential benefits of this method in improving motor skills.

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Key information

Age range

18 year–36 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Poznań University of Physical Education

Poznan, 61-871, Poland

About this study

Cryostimulation is one of the methods of post-exercise recovery, involving short-term (3 min) exposure of the body to extremely low temperatures, oscillating between -100°C and -190°C. The purpose of this therapy is to reduce inflammation, reduce physical and mental fatigue and use it as a passive form of preparing the body for further exercise as part of the training process.

The study was conducted to determine the effect of five days of whole-body cryostimulation (PBC) on reducing inflammation and improving motor skills in soccer players. A group of 24 football players was randomly divided into a test group (PBC; -140°C ± 20°C, 3 min, 5 days) and a control group (CON). Before the cryostimulation session, both groups were subjected to visual-motor ability tests, which were repeated on the last day of the study. Blood samples were collected at four time points (P0-1 day, P1-3 day, P2-5 day, P3-2 days after the test). Levels of creatine kinase (CK), tumor necrosis factor (TNFα), interleukins (IL-6, IL-10), testosterone (T) and cortisol (C) were determined in the samples.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • athletes
  • no previous experience with systemic cryotherapy
  • any other forms of recovery or cosmetic treatments

Exclusion criteria

  • alcohol or any other stimulants
  • anti-inflammation drugs
  • injuries

Treatment and study plan

Criostymulation

Other

Method: Cryosauna. Temperature: -160°C. Duration: 5 days. Session Timing: 9:00 a.m.

Session Length: 3 minutes per day

Primary outcomes

  1. IL-6 (Interleukin-6)

    Time frame: Before, after 3 days and 5 days of cryostimulation

    Immunoenzymatic assay method using a diagnostic ELISA Kit

  2. TNF-alpha (Tumor necrosis factor-alpha)

    Time frame: Before, after 3 days and 5 days of cryostimulation

    Immunoenzymatic assay method using a diagnostic ELISA Kit

  3. IL-10 (Interleukin-10)

    Time frame: Before, after 3, and 5 days of cryostimulation

    Immunoenzymatic assay method using a diagnostic ELISA Kit

  4. CK (creatine kinase)

    Time frame: Before, after 3, and 5 days of cryostimulation

    Immunoenzymatic assay method using a diagnostic ELISA Kit

  5. Cortisol

    Time frame: Before, after 3, and 5 days of cryostimulation

    Immunoenzymatic assay method using a diagnostic ELISA Kit

  6. Testosterone

    Time frame: Before, after 3, and 5 days of cryostimulation

    Immunoenzymatic assay method using a diagnostic ELISA Kit

Secondary outcomes

  1. Anthropometric measurments

    Time frame: Before, after 3, and 5 days of cryostimulation

    Analysis of body composition, Tanita BC-418

Sponsors and collaborators

Lead sponsor

Poznan University of Physical Education

Other

Registry information

Official study title

The Influence of Cryostimulation on Reducing Inflammation and Improving Motor Skills in Football Player

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Aug 12, 2024
Registry last updated
Jan 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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