Balikesir University
Balıkesir, 10145, Turkey (Türkiye)
NCT Number: NCT07299396
Alveolar recruitment manoeuvre plays a key role in the prevention of atelectasis. In addition, it affects haemodynamic parameters. This study aims to investigate the effects of RM on haemodynamic parameters using minimally invasive monitoring techniques.
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Notify Me18 year–70 year
Female
Observational
Balıkesir, 10145, Turkey (Türkiye)
During laparoscopic hysterectomy, pneumoperitoneum is created with carbon dioxide (CO₂) to provide surgical field of view and the patient is placed in Trendelenburg position. This increases intrathoracic pressure, decreases lung compliance and increases the risk of atelectasis. Therefore, lung protective ventilation strategies such as alveolar recruitment manoeuvre (RM), individualised PEEP application and low tidal volume are recommended. RM aims to increase lung compliance and prevent atelectasis by reopening collapsed alveoli. However, changes in haemodynamic parameters, especially mean arterial pressure and cardiac output, may occur during RM. In addition to standard monitoring for the management of these changes, haemodynamic evaluation can be performed with minimally invasive methods such as arterial waveform analysis. In this study, we aimed to evaluate the effects of RM applied during laparoscopic hysterectomy on intraoperative haemodynamic parameters using arterial waveform analysis.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: perioperatively
measurement of heart rate in bpm
Time frame: perioperatively
blood pressure measurement in mmmercury
Time frame: intraoperatively
Cardiac Index measurement via an arterial cannula as l/min/m2
Time frame: intraoperatively
SVI measurement via arterial cannula as L/min/m2
Time frame: intraoperatively
pulse pressure variability measured by finger probe as cm/s
Time frame: intraoperatively
systemic vascular resistance index(SVRI) measurement via arterial cannula as L/min/m2
Time frame: intraoperatively
cardiac power index(CPI) measurement via arterial line as ml/min/m2
Time frame: intraoperatively
measurement of dynamic compliance by Ventilator as Cdyn
Time frame: İntraoperatively
measurement of oxygenation via obtaining partial blood oxygene pressure via arterial blood sample pulse oxymeter as %
Time frame: postoperative day 1 and 3
assessment of pulmonary complications
Balikesir University
Other
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