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OpenTrials
Completed

NCT Number: NCT04114123

The Development of Reward Response to Food in Infancy

In this study the researchers want to learn more about reward-driven eating behavior in children ages 2 to 18 months. The researchers hope to use this knowledge to help inform obesity prevention programs.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Michigan

Ann Arbor, Michigan, 48109, United States

About this study

The study will comprise two arms and each arm has a different time perspective. The longitudinal arm is prospective in nature and the cross-sectional arm has a cross-sectional time perspective. The video observation is completed at a single time point (although standardized by inclusion criteria).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

For the Longitudinal Arm:

Inclusion criteria

  • Baby is alive
  • Baby is 6 to 16 weeks old at time of enrollment
  • Baby and mother receive care at Michigan Medicine, and specifically:
  • Baby was born at Michigan medicine
  • Baby has had a 2 month well child check
  • Mother received prenatal care at Michigan Medicine
  • Mother has a linked patient profile to baby's profile
  • Baby has a length and weight measurement on record
  • Mother is English speaking

Exclusion criteria

  • Baby is a foster child
  • Baby was still in hospital 4 days after birth
  • Baby has severe perinatal or neonatal medical problems
  • Baby has severe developmental delays
  • Multiple births

For the Cross Sectional:

Inclusion criteria

  • Enrolled in longitudinal arm of study
  • Eligible to complete all three protocols (Two Oatmeal and Reaching) as per protocol screeners
  • Baby is alive
  • Baby is 5 to 7 months old at the time of enrollment
  • Mother is biological mother
  • Mother is legal guardian
  • Mother is English speaking

Exclusion criteria

  • Baby had severe perinatal or neonatal medical problems
  • Baby currently has severe medical problems
  • Baby has severe developmental delays
  • Mom had severe complications during pregnancy
  • Multiple Births
  • Food allergies

Treatment and study plan

Primary outcomes

  1. Association of trajectory membership and body mass index z-score (BMIz)

    Time frame: Time Frame: 24 months

    Trajectory membership could be "wanting", "salience", or "liking"

Other outcomes

  1. Association of reward-driven eating component wanting with maternal and infant characteristics

    Time frame: Up to 18 months

  2. Association of reward-driven eating component salience with maternal and infant characteristics

    Time frame: Up to 18 months

  3. Association of reward-driven eating component liking with maternal and infant characteristics

    Time frame: Up to 18 months

  4. Association of maternal and infant characteristics and weight-for-length z-score (WLZ)

    Time frame: 2 months through 24 months

  5. Association of infant reward-driven eating and weight-for-length z-score (WLZ)

    Time frame: 2 months through 24 months

  6. Association of infant reward-driven eating and infant diet

    Time frame: Up to 18 months

  7. Association of infant reward-driven eating and infant weight-for-length z-score (WLZ)

    Time frame: 6 months through 24 months

  8. Association of infant diet and infant weight-for-length z-score (WLZ)

    Time frame: 6 months through 24 months

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Collaborators

  • American Heart Association

Registry information

Important dates

Study start
2019
Primary completion
2024
Study completion
2024
First posted
Oct 3, 2019
Registry last updated
Nov 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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