Skip to main content
OpenTrials
Completed

NCT Number: NCT04464343

The Biomechanical Mechanism for Gait and Plantar Pressure Changes After Posterior Cruciate Ligament Rupture and Reconstruction

Investigating the biomechanics for the PCL ruptured or reconstructed patients during walking, jogging, cutting, jumping. To establish a knee joint biomechanical evaluation model to quantify and evaluate the plantar pressure information under dynamic load-bearing state after PCL fracture. Provide a precise basis for the biomechanical state of the knee, and establish a clinically practical automatic analysis of plantar pressure information and an expert diagnostic system.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Peking University Third Hospital

Beijing, 100191, China

About this study

Background: The posterior cruciate ligament (PCL) is an essential structure in knee stabilization. Knee cartilage degeneration after a PCL injury has been reported in several studies. Understanding the changes in movement patterns of patients with PCL ruptures could help clinicians make specific treatment protocols to restore patients' sporting ability and prevent joint degeneration. However, the kinematics and kinetics of the lower limb in patients with PCL injuries are still not clear.

Methods: Three-dimensional gait analysis system, force plate, electromyography will be used for 55 healthy male participants (control group) and 55 male patients with isolated PCL-deficiency (PCL-d group) during walking, jogging, cutting, jumping. Repeated measurement two-factor analysis of variance will be performed to determine differences between involved and uninvolved legs in the PCL-d group and control group at different rehabilitation times (prior reconstruction surgery, 6 months, and 1-year post PCL reconstruction surgery). Three-dimensional gait analysis and computer-aided analysis technology of plantar pressure information were used to study the changes of PCL after fracture and reconstruction. Based on the plantar pressure information, the movement parameters, and individual attribute parameters, establish a knee joint biomechanical evaluation model to quantify and evaluate the plantar pressure information under dynamic load-bearing state after PCL fracture. Provide a precise basis for the biomechanical state of the knee, and establish a clinically practical automatic analysis of plantar pressure information and an expert diagnostic system.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age of 18-45 years old
  • Isolated PCL rupture patients: The inclusion criteria included an isolated PCL rupture of at least 3 months' duration.
  • Healthy volunteers: no history of neuro or musculoskeletal system injury that may affect the movements.

Exclusion criteria

  • additional knee ligament or meniscal damage
  • severe damage to the ipsilateral hip, ankle joint, or contralateral lower limb (ligament ruptures or bone fractures)
  • age >50 years (to avoid age-induced osteoarthritis interference)
  • any cartilage injury grade >2 according to the Outerbridge classification
  • Tegner score18 <3

Treatment and study plan

No intervention

Other

This is an observation study, with no intervention

Primary outcomes

  1. walking speed

    Time frame: On the day of enrollment.

    Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

  2. ground reaction force

    Time frame: On the day of enrollment.

    Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

  3. knee flexion angle

    Time frame: On the day of enrollment.

    Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

  4. the moment of knee extension in the gait cycle

    Time frame: On the day of enrollment.

    Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

  5. the moment of knee flexion in the gait cycle

    Time frame: On the day of enrollment.

    Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

Secondary outcomes

  1. The International Knee Documentation Committee (IKDC) score

    Time frame: On the day of enrollment.

    The International Knee Documentation Committee (IKDC) score was used to evaluate the knee health.The patients completed score by themselves. The lowest score is 0 and the highest score is 100. The higher is better.

Sponsors and collaborators

Lead sponsor

Peking University Third Hospital

Other

Registry information

Important dates

Study start
2014
Primary completion
2018
Study completion
2018
First posted
Jul 9, 2020
Registry last updated
Jul 9, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.