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OpenTrials
Completed

NCT Number: NCT04767685

The Bern Perioperative Biobank

The goal of the research is to define clinically relevant molecular markers for increased risk of peri-/ postoperative organo-dysfunctions, inflammation, adverse events and disease progression. To better understand the perioperative impact the investigators aim to determine perioperative levels of molecular markers over time in the available samples and clinical data of the Bern perioperative Biobank (BPBB) cohort to finally increase quality of perioperative care of patients by permitting preventive measures to be taken early in patients at risk.

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Key information

Conditions

Anesthesia Surgical Procedure, Operative

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern

Bern, 3010, Switzerland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years and older
  • Written informed consent
  • Non-emergency surgery

Exclusion criteria

  • Transient incapacity to consent or insufficient time (< 6h) to consider study participation
  • No informed consent
  • Cognitive impairment/Patients unable to consent
  • Patients who retrospectively expressed their wish to be excluded

Treatment and study plan

Primary outcomes

  1. Assessing the change of the metabolic profile in the perioperative setting

    Time frame: Before induction of anesthesia as baseline

    Surgery causes significant disruption of physiologic metabolism. The investigators currently lack specific markers to assess change of the metabolic profile in the perioperative setting. The investigators aim to identify metabolic markers and their change in the perioperative period in association with patients' clinical outcome.

  2. Assessing the change of the metabolic profile in the perioperative setting

    Time frame: Ca. 2-5hours later upon finishing the surgery

    Surgery causes significant disruption of physiologic metabolism. The investigators currently lack specific markers to assess change of the metabolic profile in the perioperative setting. The investigators aim to identify metabolic markers and their change in the perioperative period in association with patients' clinical outcome.

  3. Assessing the change of the metabolic profile in the perioperative setting

    Time frame: On postoperative day 1 during the morning round between 07:30-9:00am

    Surgery causes significant disruption of physiologic metabolism. The investigators currently lack specific markers to assess change of the metabolic profile in the perioperative setting. The investigators aim to identify metabolic markers and their change in the perioperative period in association with patients' clinical outcome.

Sponsors and collaborators

Lead sponsor

Insel Gruppe AG, University Hospital Bern

Other

Registry information

Official study title

The Bern Perioperative Biobank to Define Perioperative Changes of Molecular Markers of Perioperative Organo-dysfunctions, Inflammation, Adverse Events and Disease Progression

Acronym: BPBB

Important dates

Study start
2011
Primary completion
2021
Study completion
2021
First posted
Feb 23, 2021
Registry last updated
Nov 15, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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