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Completed

NCT Number: NCT04344340

The Association Between MIH and HSPM

Aim of the Study Evaluate association between HSPM and MIH in Egyptian children. Record the prevalence of HSPM and MIH in Egyptian children

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Key information

About this study

Statement of the Problem:

Molar Incisor Hypomineralization (MIH) is defined as developmental qualitative defect of systemic origin, which affects one to four of first permanent molars and frequently associated with permanent incisors . The prevalence of MIH worldwide was reported from 2.4% to40.2% and clinical measures of MIH based on scientific criteria was established based on the European Academy of Pediatric Dentistry criteria to allow comparison between the findings of different studies .

The most commonly reported clinical problems for patients with MIH are hypersensitivity of teeth to various thermal and mechanical stimuli result in improper tooth brushing, plaque accumulation and rapid caries progression. Severely affected enamel shows post eruptive breakdown and such teeth require extensive treatment, ranging from prevention to restorations and extractions. MIH patients also have increased risk of developing dental fear and anxiety as well as behavior management problems added to the difficulty to achieve effective local anaesthesia which are related to chronic pulp inflammation from dentin exposure due to excessive enamel breakdown.

Rational As developmental of Second Primary Molar start at the same time as the development of the first permanent molars and incisor but the maturation of permanent teeth occur more slow. So when a systemic disturbance occur it affect second primary molar as well as first permanent molar and incisors.

Few studies test the association between hypomineralized second primary molar (HSPM) and MIH. While no study available on Egyptian children.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children aged from 8 to 9 years.
  • Both genders.
  • No systemic health problems

Exclusion criteria

  • Children with extracted primary second molars and permanent incisors and molars.
  • Children with history of dental trauma.
  • Children with orthodontic bands or dental appliances

Treatment and study plan

clinical examination

Diagnostic Test

clinical examination

Primary outcomes

  1. The prevalence of hypomineralized second primary molars.

    Time frame: 1 year

    The percentage of children who has enamel defect on their second primary molars in the study

Secondary outcomes

  1. the prevalence of Molar Incisor Hypomineralization

    Time frame: 1 year

    The percentage of children who has enamel defect on their permenant molars and Incisors at this study

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2022
First posted
Apr 14, 2020
Registry last updated
Jan 25, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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