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NCT Number: NCT06766370

The Application of Multimodal Ultrasound Imaging in Carpal Tunnel Syndrome

The aim of this study is to explore the application value of multimodal ultrasound parameters in the diagnosis and treatment follow-up of Carpal Tunnel Syndrome.

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Key information

Conditions

Carpal Tunnel Syndrome (CTS) Carpal Tunnel Syndrome Cumulative Trauma Disorders Median Neuropathy Mononeuropathies Nerve Compression Syndromes Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Sprains and Strains Wounds and Injuries

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 70 years;
  • Presence of sensory abnormalities and motor dysfunction in the median nerve distribution area;
  • Positive Tinel's sign or Phalen's test;
  • Neurophysiological examination consistent with mild to moderate Carpal Tunnel Syndrome.-

Exclusion criteria

  • Severe Carpal Tunnel Syndrome;
  • Concurrent rheumatic, metabolic, systemic, or other systemic diseases;
  • Concurrent cervical spondylosis or other peripheral neuropathies;
  • Wrist joint trauma, surgery, space-occupying lesions, or nerve itself with space-occupying lesions;
  • Concurrent malignant tumors or severe cardiopulmonary diseases;
  • History of previous wrist surgery or injections;
  • Pregnancy;
  • Allergy to corticosteroids or local anesthetics.-

Treatment and study plan

Ultrasound-guided nerve hydrodissection treatment

Procedure

Under ultrasound guidance, a mixed solution of corticosteroids and local anesthetics is injected around the nerve, followed by release of the transverse carpal ligament.

Primary outcomes

  1. Boston Carpal Tunnel Syndrome Questionnaire ，BCTQ

    Time frame: 1,3,6,12 months

    The Boston Carpal Tunnel Score is a patient-reported questionnaire that examines symptom severity and overall functional status of patients with carpal tunnel syndrome. The Symptom Severity Scale (SSS) with 11 questions is scored on a Likert scale of 1-5 and the Functional Status Scale (FSS) with 8 questions is scored from 1-5 with 1 as no difficulty and 5 as difficult.The higher scores mean a worse outcome.

Secondary outcomes

  1. the patient's sensory nerve conduction velocity (SNCV)

    Time frame: 3,6,12months

    SNCV in m/s

  2. the patient's distal motor latency (DML).

    Time frame: 3,6,12months

    DML in ms

Study contacts

Contact information is provided by the study sponsor or research team.

Nanjing Trum Tower Hospital

CONTACT

[email protected]

15651890325

Sponsors and collaborators

Lead sponsor

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2028
First posted
Jan 9, 2025
Registry last updated
Jan 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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