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Completed

NCT Number: NCT07194031

The Acute Effects of Ankle Exercises on Knee Proprioception

The goal of this randomized research study is to investigate the acute effects of ankle exercises on improving knee proprioception and pain in individuals with knee pain, aged 18-70, who receive intervention-based ankle and knee exercises to treat their knee pain. The main question it aims to answer is:

• Does ankle exercise affect knee joint proprioception and pain in individuals with knee pain? Researchers will compare ankle exercise (the intervention) with knee exercise (as part of their regular medical care for knee pain) to determine if ankle exercise is effective in improving knee joint proprioception and reducing pain.

Participants will be asked to do exercises and to let the researchers take their measurements.

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Key information

Conditions

Knee Pain Chronic Behavior Motor Activity Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Gaziantep Islam Science and Technology University

Gaziantep, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The participants who have a VAS pain score >5,
  • The participants who have experienced knee pain for the last six months or longer,
  • The participants who volunteered to participate in the study

Exclusion criteria

  • Individuals who had undergone knee and ankle surgery within the last year
  • Individuals who have a VAS pain score below 5
  • Individuals who are experiencing ROM limitations in the knee or ankle
  • Individuals who have a neurological pathology in the lower extremity

Treatment and study plan

Ankle Exercise

Other

In the literature, studies have evaluated ankle proprioception following interventions applied to the knee. However, no studies report the effects of ankle exercises on knee proprioception

Other names: Plantar flexion

Knee Exercise

Other

The literature emphasizes that long-term and multidirectional exercise programs provide proprioceptive improvements

Other names: Knee flexion-extension

Primary outcomes

  1. Knee proprioception

    Time frame: 4 weeks

    Knee flexion- extension position

Secondary outcomes

  1. Knee pain

    Time frame: 4 weeks

    Visual Analogue Scale (VAS); Zero, no pain; 10 worst pain

Sponsors and collaborators

Lead sponsor

Gaziantep Islam Science and Technology University

Other

Registry information

Official study title

The Acute Effects of Ankle Exercises on Knee Proprioception and Pain in Individuals With Knee Pain

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 26, 2025
Registry last updated
Sep 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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