Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT06765044

Textbook Outcomes in Urgent Appendectomy

A "textbook outcome" patient is defined as one whose surgical course is uneventful, with no complications, readmissions, or mortality. There is a lack of published research regarding textbook outcomes with an acute appendicitis that are treated with an appendectomy.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

About this study

The objective of this study is to analyze the attainment of textbook outcomes (TO) in patients undergoing urgent appendicectomy (UA) for acute appendicitis and to identify the factors associated with achieving TO.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Acute Appendicits in older than 18 years old
  • Acute Appendicitis that needs appendectomy

Exclusion criteria

  • Age under 18 years old
  • Other diagnostic than an Acute Appendicitis

Treatment and study plan

Primary outcomes

  1. Textbook Outcomes

    Time frame: 2022-2024

    Classical assessments, focused solely on mortality and morbidity, are increasingly considered insufficient. A more comprehensive approach, using composite measures, offers a more accurate evaluation, providing a multidimensional view and patient-centred healthcare appraisal. The textbook outcome (TO) is the most used objective composite measure to compare surgical quality across centres

Secondary outcomes

  1. Appendectomy in less than 24h

    Time frame: 2022-2024

    From diagnostic of Acute Appendicitus to Surgical Treatment should be less than 24h

  2. Hospital Stay less than 5 days

    Time frame: 2022-2024

    Optimal hospital stay should be less than 5 days

  3. Intraoperative incidences

    Time frame: 2022-2024

    Intraoperative bleeding, perforation of the appendix, iatrogenic injury to other structures

  4. Short antibiotics treatment

    Time frame: 2022-2024

    Less than 72h of antibiotic treatment

  5. Patient comorbidities

    Time frame: 2022-2024

    Charlson Comorbidity Index

  6. Surgical Risk

    Time frame: 2022-2024

    ASA Scoring System

  7. Intraoperative appendicitis gradding

    Time frame: 2022-2024

    AAST classification AAST I: Acutely inflamed appendix, intact. AAST II:Gangrenous appendix, intact AAST III:Above, with evidence of local contamination AAST IV:Above, with abscess or phlegmon in region of appendix AAST V:Above, with addition of generalized purulent contamination away from appendix

    WSES Classification:

    Grade- 0 (normal looking) Grade-1 (inflamed) Grade- 2A and 2B (necrosis) Grade- 3A - 3B - 3C (perforated - inflammatory tumor) Grade- 4 (perforate - diffuse peritonitis)

  8. Postperative complications

    Time frame: 2022-2024

    Clavien Dindo and CCI (https://www.cci-calculator.com/)

    Grade I: Any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic, and radiological interventions.

    Grade II:Requiring pharmacological treatment with drugs other than such allowed for Grade I Grade III:Requiring surgical, endoscopic or radiological intervention. Grade IV:Life-threatening complication (including CNS complications)* requiring IC/ICU-management with single or multiorgan disfunction.

    Grade V: Death of a patient

  9. Readmision index

    Time frame: 2022-2024

    Percentage of readmission

Study contacts

Contact information is provided by the study sponsor or research team.

Ana Maria Gonzalez Castillo PhD, PhD

CONTACT

[email protected]

+34665126866

Ana Maria González Castillo PhD, PhD

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Hospital del Mar

Other

Registry information

Official study title

Textbook Outcomes of Surgical Treatment of Acute Appendicitis

Acronym: APPX_TEXTBOOK

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 9, 2025
Registry last updated
Jan 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.