Testing an Herbal Pain Relief Patch to Reduce Pain in Cancer Survivors

Inclusion criteria

• Age ≥ 18 years or older
• A diagnosis of cancer with no restrictions placed on type of cancer or stage. Eligibility criteria will not be restricted to MSK confirmed biopsy/diagnosis. Participating institution's testing is sufficient for other study sites
• Completed active treatment (surgery, chemotherapy, and/or radiotherapy) at least one month prior to study initiation (patients on continued hormone treatment or maintenance targeted therapies will not be excluded).
• Patients currently have no evidence of disease
• Ambulatory (Karnofsky functional score of ≥ 60)
• Having a focused location of regional musculoskeletal pain (e.g. joints, extremities, back, neck) that can be covered by one patch of PRP
• Worst pain score (numeric pain rating scale) 5 or above in the preceding week
• Pain for at least 3 months and at least 15 days with pain in the preceding 30 days; and willingness to adhere to and understanding of all study-related procedures, including randomization to one of the two possible choices
• Able to understand informed consent and provide signed informed consent form

Exclusion criteria

• Patients with non-musculoskeletal pain syndromes (headache, facial pain, chest pain, visceral abdominal pain) will be excluded if these are the sole source of pain but can be present as co-morbid conditions as long as a patient has a primary musculoskeletal pain condition defined as above.
• Patients have generalized musculoskeletal pain such as fibromyalgia
• Use of corticosteroid drugs by any route of administration within 30 days
• Patients with significant self-reported skin disorders
• Patients with open wounds, infections, skin trauma at skin overlying area of pain
• Patients with documented history of skin sensitivity to adhesive or allergic reaction to other patches or topical analgesics
• Patients with documented skin allergic reaction to plants or herbs
• Patients who are in active treatment (chemotherapy, surgery, radiotherapy)
• Plan to change or initiate other pain medications or interventions (e.g. physical therapy, acupuncture, injection). Patients may remain on their current pain regimen.