University of Utah
Salt Lake City, Utah, 84112, United States
Location status: Recruiting
Recruiting
NCT Number: NCT07577765
Testing a Tailored Approach to Long-Term Weight Loss Success
The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight. The main questions it aims to answer are:
* Is an adaptive intervention with tailored re-engagement support feasible for individuals following intentional weight loss? * Does this intervention prevent weight regain after intentional weight loss?
Participants will:
* Complete a baseline assessment of body measurements * Complete surveys on dietary intake, mental health, and physical activity
Participants will also engage in a 26-week program, which involves:
* Receive regular educational texts/emails * Fill out weekly online survey check-ins * Weigh themselves at least weekly on a scale provided by the study * Some participants may receive health coaching during portions of the study. * Assessments will be repeated for all participants at the end of the intervention period.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year–65 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- BMI of ≥ 27 prior to weight loss
- Lost ≥ 7% of body mass in the past 6 months
- Weight loss was intentional
- No plans for weight loss surgery in the next 6 months
- Access to a smart device that can download applications and receive text messages
- Able to receive clearance for study participation from primary care provider
Exclusion criteria
- Pregnant or within 12 months postpartum, or planning pregnancy
- Uncontrolled conditions that affect overall health (cardiovascular, metabolic, renal, pulmonary, psychiatric, thyroid, cancers)
- Food insecure
- Bariatric surgery or cancer treatment within the past 5 years
- Active or recent (<12 months) treatment/diagnosis of an eating disorder
Treatment and study plan
Adaptive weight regain prevention
BehavioralAdaptive intervention that will tailor participant re-engagement with professional support (e.g. health coaches) based on behavioral triggers and anthropometric monitoring (diet changes, weight increase, failure to weigh weekly).
Primary outcomes
-
Feasibility - Participant Retention
Time frame: From enrollment to the end of the 26-week monitoring period
Number of participants who continue to participate for all 26 weeks of the study and complete all study activities
-
Feasibility - Participant Adherence
Time frame: From enrollment to the end of the 26-week monitoring period
Number of participants who complete all study activities, including weekly weigh-ins, weekly surveys, and pre/post study visits.
-
Efficacy - Participant Weight
Time frame: From enrollment to the end of the 26-week monitoring period
-
Efficacy - Participant Dietary Intake
Time frame: From enrollment to the end of the 26-week monitoring period
Dietary and nutritional data collected via self-report using the ASA24 (Automated Self-Administered 24-Hour Dietary Assessment Tool). This includes calories, protein, fats, and other nutrition information based on participant self-report of meals.
-
Efficacy - Eating Self-Efficacy in High-Risk Situations
Time frame: From enrollment to the end of the 26-week monitoring period
Eating self-efficacy in high-risk situations will be measured pre- & post-intervention using the Weight Efficacy Lifestyle Questionnaire.
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Efficacy - Eating Behavior Patterns
Time frame: From enrollment to the end of the 26-week monitoring period
Eating behavior patterns will be measured pre- & post-intervention using the Three-Factor Eating Questionnaire.
-
Efficacy - Sleep/Rest Duration
Time frame: From enrollment to the end of the 26-week monitoring period
Sleep/rest duration will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
-
Efficacy - Daily Step Count
Time frame: From enrollment to the end of the 26-week monitoring period
Daily step count will be measured using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
-
Efficacy - Sedentary Behavior (Sitting/Lying Time)
Time frame: From enrollment to the end of the 26-week monitoring period
Sedentary behavior will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
-
Efficacy - Standing Time
Time frame: From enrollment to the end of the 26-week monitoring period
Standing time will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
University of Utah
Other
Collaborators
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry information
Official study title
Pilot Testing an Adaptive Intervention for Weight Loss Maintenance
Important dates
- Study start
- 2026
- Primary completion
- 2027
- Study completion
- 2027
- First posted
- May 11, 2026
- Registry last updated
- May 11, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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