Skip to main content
OpenTrials
Completed

NCT Number: NCT05778344

Teletechnology-assisted Home-based Exercise Program for Severe COVID-19

The aim of this study was to investigate the efficacy of a home-based pulmonary rehabilitation program with the support of teletechnology in COVID-19 survivors. The main questions it aims to answer were:

* The change of six-minute walk distance * The change of time of one-minute sit-to-stand test * The change of maximal strength of upper-limb, lower-limb and respiratory muscle * The change of quality of life Participants in the home-based pulmonary rehabilitation group received teletechnology-assisted consultations (either by videotelephony or telephone calls) for every 1-2 weeks during the intervention period, and participants in the usual care group did not receive teletechnology-assisted consultations during the intervention period.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Nidovirales Infections Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Telerehabilitation Virus Diseases

Age range

20 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

National Taiwan University Hospital

Taipei, 100, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients are 20 years or more with severe (severe pneumonia) to critical (acute respiratory distress syndrome, sepsis, or septic shock) COVID-19 during hospitalization after deisolation.
  • Patients are 65 years or more, or ever receiving oral antiviral treatment after deisolation.
  • Patient have the ability to ambulate on level surface without direct contact of another person, have telecommunication device(s), and provide consent to receive teletechnology-assisted rehabilitation.

Exclusion criteria

  • Patients are pregnant or planning for pregnancy.
  • Patients have cognitive dysfunction, learning disability, uncontrolled arrhythmia or hypertension, or any medical diagnosis other than COVID-19 that would prominently influence their ability to follow instructions and perform exercise.

Treatment and study plan

Teletechnology-assisted home-based pulmonary rehabilitation

Behavioral

The accuracy and safety of home-based pulmonary rehabilitation will be checked regularly through technology devices such as smart watch and via videotelephony (or telephone calls if indicated).

Primary outcomes

  1. Six-minute walk distance

    Time frame: Week 0

    The distance of six-minute walk test

  2. Six-minute walk distance

    Time frame: Week 4

    The distance of six-minute walk test

  3. Six-minute walk distance

    Time frame: Week 8

    The distance of six-minute walk test

  4. Six-minute walk distance

    Time frame: Week 12

    The distance of six-minute walk test

  5. Six-minute walk distance

    Time frame: Week 24

    The distance of six-minute walk test

Secondary outcomes

  1. Maximal upper limb strength

    Time frame: Week 0

    Hand grip strength

  2. Maximal upper limb strength

    Time frame: Week 4

    Hand grip strength

  3. Maximal upper limb strength

    Time frame: Week 8

    Hand grip strength

  4. Maximal upper limb strength

    Time frame: Week 12

    Hand grip strength

  5. Maximal upper limb strength

    Time frame: Week 24

    Hand grip strength

  6. Maximal lower limb strength

    Time frame: Week 0

    Leg press strength

  7. Maximal lower limb strength

    Time frame: Week 4

    Leg press strength

  8. Maximal lower limb strength

    Time frame: Week 8

    Leg press strength

  9. Maximal lower limb strength

    Time frame: Week 12

    Leg press strength

  10. Maximal lower limb strength

    Time frame: Week 24

    Leg press strength

  11. Maximal respiratory muscle strength

    Time frame: Week 0

    Inspiratory and expiratory pressure of respiratory muscle

  12. Maximal respiratory muscle strength

    Time frame: Week 4

    Inspiratory and expiratory pressure of respiratory muscle

  13. Maximal respiratory muscle strength

    Time frame: Week 8

    Inspiratory and expiratory pressure of respiratory muscle

  14. Maximal respiratory muscle strength

    Time frame: Week 12

    Inspiratory and expiratory pressure of respiratory muscle

  15. Maximal respiratory muscle strength

    Time frame: Week 24

    Inspiratory and expiratory pressure of respiratory muscle

  16. Quality of life score

    Time frame: Week 0

    Quality of life assessed by Short-form 12 questionnaire

  17. Quality of life score

    Time frame: Week 4

    Quality of life assessed by Short-form 12 questionnaire

  18. Quality of life score

    Time frame: Week 8

    Quality of life assessed by Short-form 12 questionnaire

  19. Quality of life score

    Time frame: Week 12

    Quality of life assessed by Short-form 12 questionnaire

  20. Quality of life score

    Time frame: Week 24

    Quality of life assessed by Short-form 12 questionnaire

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

Efficacy of Teletechnology-assisted Home-based Exercise Program for Severe COVID-19

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Mar 21, 2023
Registry last updated
Sep 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.