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Completed

NCT Number: NCT07058818

Tailored Resistance Training After Adverse Pregnancy Outcomes

Approximately 7-10 postpartum people with recent adverse pregnancy outcomes (APOs: preeclampsia, gestational diabetes, hypertensive disorders of pregnancy, fetal growth restriction or low birth weight baby, or preterm birth) will be invited to complete 4 weeks of a resistance training intervention, including associated incentives, communication, and marketing materials.

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Key information

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

School of Kinesiology

Ann Arbor, Michigan, 48109, United States

About this study

People who had APOs have a higher risk of heart disease and diabetes in the future. Resistance training might help lower risk of heart disease and diabetes in people who had APOs, but it can be difficult for postpartum people to perform exercise as they are juggling demands of a new baby and healing from pregnancy and child birth. The goal of this project is to find an exercise plan that works for individuals who recently gave birth. This study will determine whether a resistance training intervention co-designed by researchers and postpartum individuals is do-able for individuals who recently had APOs.

Participants in this trial will have height and weight measured. One exercise session, including a warm-up, resistance training, and cool-down with stretching will be completed in the School of Kinesiology at the University of Michigan. Then participants will receive an exercise program to perform over the next 4 weeks. An exercise session at around the midpoint of the program will be supervised by a trainer as a check point. They will receive a text or email message every day for those 4 weeks asking them to reply and tell the study team if they did the resistance training and if they did the program as it was written (as prescribed).

A few survey questions about participants mood regarding physical activity before and after exercise and belief in the ability to continue to exercise at the beginning and end of the intervention will be asked. Some questions regarding what participants thought about the marketing materials and the exercise program in general will be asked at the end of the intervention.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Had a single baby in your most recent pregnancy
  • Are 18-45 years old
  • Are 3-15 months postpartum
  • Are not currently pregnant
  • Had an adverse pregnancy outcome/medical complication in your most recent pregnancy, including preeclampsia, gestational diabetes, hypertensive disorders of pregnancy, fetal growth restriction or low birth weight baby, or preterm birth
  • Your doctor told you that you are able to participate in exercise
  • Are not currently meeting national physical activity guidelines, defined as 150 min/wk of aerobic exercise and 2 resistance training sessions/wk
  • Can attend a visit at the University of Michigan's School of Kinesiology Building
  • Are willing to perform resistance exercise twice a week for 4 weeks
  • Are willing to receive and respond to a daily message sharing whether you completed resistance exercise that day and completed it as recommended

Exclusion criteria

  • Had a multiple birth (twins, triplets, etc) in your most recent pregnancy
  • Are <18 or >45 years old
  • Are <3 months or >15 months past your last birth
  • Are currently pregnant
  • Are unable to exercise or have been told by a healthcare provider not to exercise
  • Are currently meeting national physical activity guidelines, defined as 150 min/wk of aerobic exercise and 2 resistance training sessions/wk
  • Did not have an adverse pregnancy outcome, including preeclampsia, gestational diabetes, hypertensive disorders of pregnancy, fetal growth restriction or low birth weight baby, or preterm birth, in your most recent pregnancy
  • Are unable to attend a study visit at the University of Michigan's School of Kinesiology Building
  • Are not willing to perform 4 weeks of resistance training
  • Are not willing to receive and send daily messages

Treatment and study plan

Resistance training

Behavioral

Full-body physical therapy and resistance training intervention

Primary outcomes

  1. Adherence

    Time frame: 4 weeks

    Proportion of prescribed resistance exercise sessions completed

  2. Compliance

    Time frame: 4 weeks

    Proportion of prescribed resistance exercise sessions completed as prescribed/directed

Secondary outcomes

  1. Self-efficacy (assessed with validated survey)

    Time frame: 4 weeks

    Exercise self-efficacy survey

  2. Physical activity enjoyment (assessed with validated survey)

    Time frame: 4 weeks

    Enjoyment questionnaire

Other outcomes

  1. Opinions of exercise program

    Time frame: 4 weeks

    Program feedback provided during a semi-structured interview at the end of the intervention.

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Collaborators

  • Women's Health Innovation Fund

Registry information

Acronym: RT after APOs

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 10, 2025
Registry last updated
Apr 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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