Sweet Corn and Carotenoids

This study will assess the effect of daily yellow and white sweet corn intake on serum lutein and zeaxanthin concentrations. Skin carotenoid levels using the Veggie Meter will be assessed, and gastrointestinal symptoms and changes in fecal microbiota during a 4-week intervention period will be monitored.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Carotenoids

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Florida

Gainesville, Florida, 32611, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults ≥ 18 years of age
Able to provide written consent in English
Baseline Veggie Meter score of ≤ 300 (Scale from 0 to 850)
Willing to adhere to study procedures

Exclusion criteria

Baseline Veggie Meter score of >300
Corn allergy
Current use of laxatives or antidiarrheal medications
Previously or currently being treated for intestinal disease, including irritable bowel syndrome, Crohn's disease, ulcerative colitis, celiac disease, or gastrointestinal cancer
Previous gastrointestinal surgery (e.g., gastric bypass, fundoplication, bowel resection)
Current cancer treatment
Current pregnancy
Vegetarian diet
Elite athletes or long-distance runners.
Use of antibiotic drugs within 1 month of the screening visit.

Treatment and study plan

Yellow Sweet Corn

Dietary Supplement

Participants will consume 1.5 cups daily of yellow or white canned sweet corn.

White Sweet Corn

Dietary Supplement

1.5 cups daily of canned yellow sweet corn

Primary outcomes

Serum concentration of lutein + zeaxanthin

Time frame: 28 days

Sum of serum concentrations of lutein and zeaxanthin.

Sponsors and collaborators

Lead sponsor

University of Florida

Other

Registry information

Official study title

Effects of Sweet Corn Intake on Carotenoid Levels and Gastrointestinal Wellness

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Mar 24, 2025
Registry last updated: May 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting