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OpenTrials
Completed

NCT Number: NCT05194813

Surface Treatment of the Dental Implant on the Osseointegration

Dental implants have become a widely accepted treatment modality for the replacement of missing single or multiple teeth in the recent years. In order to meet patients' needs for shorter treatment times and the necessity of dealing with more challenging clinical situations, implants and implant therapies have undergone continuous improvement to improve the function and longevity of the implants. Recently the constant search for improvements in modern implant have been focused on surface modifications so a new era of surface treatment have been showed up; the chemically modified hydrophilic surfaces.

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Key information

Conditions

Dental Implants Surface Treatment

Age range

20 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Alexandria Faculty of Dentistry

Alexandria, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Missing mandibular posterior teeth.
  • Good oral hygiene (plaque index less than 10 %)
  • Good compliance to the treatment.
  • Participants are free from local or systemic disease
  • Willingness and ability to commit to follow-up placement.
  • Adequate bone height and width to accommodate implant placement and sufficient keratinzed mucosa.
  • At least 3months after tooth extraction
  • Sufficient interocclusal distance

Exclusion criteria

  • Presence of persistent and unresolved infection in the implant site
  • Parafunctional habits.
  • Heavy Smokers.
  • Uncontrolled systemic disease that impedes bone healing

Treatment and study plan

Aqua alvim CM, neodent implant (Test)

Other

Acqua, Hydrophilic sandblasted, and acid-etched dental implants

Neoporous alvim CM, neodent implant (Control)

Other

Neoporous, Hydrophilic sandblasted, and acid-etched dental implants

Primary outcomes

  1. Change in implant stability

    Time frame: at baseline and 6 months

    The implant stability measurement was examined at the time of insertion of the implants (primary stability) and 6 months (secondary stability) for the two groups of patients using the resonance Frequency Analysis (RFA) via the Osstell ISQ system

  2. Change in bone density

    Time frame: at baseline and 6 months

    Cone beam Computerized tomography was used to assess bone denisty

  3. Change in ridge height

    Time frame: at baseline and 6 months

    Cone beam Computerized tomography was used to assess ridge height

  4. Biochemical assessment of bone formation

    Time frame: at 3 months

    Done by measuring of Runt-related transcription factor 2 (RUNX2) as a bone marker by Enzyme-Linked Immunosorbent Assay

Sponsors and collaborators

Lead sponsor

Hams Hamed Abdelrahman

Other

Registry information

Official study title

The Effect of Surface Treatment of the Dental Implant on the Osseointegration in Mandibular Posterior Missing Teeth

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Jan 18, 2022
Registry last updated
Jan 18, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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