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Completed

NCT Number: NCT07608523

Marginal Bone Level Around Dental Implants in Periodontitis Patients

This study evaluates and compares marginal bone level changes around dental implants with two different surface characteristics in patients with a history of periodontitis. Participants will receive dental implants and will be followed up for one year to assess bone level changes around the implants.

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Key information

Conditions

Periodontitis Dental Implants Gingival Diseases Gingival Inflammation Gingivitis Infections Marginal Bone Loss Mouth Diseases Periodontal Diseases Periodontal Probing Depth Stomatognathic Diseases

Age range

35 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dental Medicine for Girls, Al-Azhar University

Cairo, Cairo Governorate, Egypt

About this study

Patients with treated periodontitis who require dental implants will be divided into two groups based on implant surface type. Marginal bone level will be assessed radiographically at baseline, then at 3 months,6 months, and 12 months after implant placement. The study aims to determine whether implant surface characteristics influence marginal bone loss in periodontitis-susceptible patients over a one-year follow-up period.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ranged from 35 to 55 years old, with a history of periodontitis
  • Presence of at least one edentulous space
  • Presence of adequate bone volume to place implants and achieves primary implant stability without the need for bone reconstructive approaches
  • Absence of systemic diseases

Exclusion criteria

  • Presence of para-functional habits
  • Chronic smokers or former smokers
  • Pregnancy and lactation
  • Any patient who is not willing to follow our treatment protocol

Treatment and study plan

SLA Dental Implant

Device

Sandblasted large-grit corundum and acid-etched (SLA) surface dental implant

Plasma Spraying Dental Implant

Device

Plasma spraying surface treated dental implant

Primary outcomes

  1. Marginal Bone Level

    Time frame: Baseline, 3 months, 6 months, and 12 months after implant placement

    Radiographic assessment of marginal bone level changes around dental implants measured in millimeters using Cone Beam Computed Tomography (CBCT)

Secondary outcomes

  1. Probing Depth

    Time frame: Baseline, 3 months, 6 months, and 12 months

    probing depth measured in millimeters around implants

  2. Gingival Index

    Time frame: Baseline, 3 months, 6 months, and 12 months

    The gingival condition around the implants were evaluated using the Löe and Silness Gingival Index. A plastic periodontal probe were used to gently assess the gingival tissues at four surfaces per implant (mesial, buccal, distal, and lingual). Each surface was scored from 0 to 3 as follows:

    0 = Normal gingiva

    • = Mild inflammation (slight change in color, slight edema, no bleeding on probing)
    • = Moderate inflammation (redness, edema, bleeding on probing)
    • = Severe inflammation (marked redness and edema, ulceration, spontaneous bleeding)

Sponsors and collaborators

Lead sponsor

Faculty of Dental Medicine for Girls

Other Gov

Registry information

Official study title

Evaluation of Marginal Bone Level Around Dental Implants With Two Types of Surface Characteristics in Periodontitis Patients

Acronym: (MBL)

Important dates

Study start
2023
Primary completion
2025
Study completion
2026
First posted
May 27, 2026
Registry last updated
Jun 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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