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OpenTrials
Completed

NCT Number: NCT00570934

Supplementation With Vitamin D, Calcium or Both on Calcium Absorption and Bone Mineral Content in Children With JRA

2000 international units (IU) vitamin D, 1 gram (gm) calcium, or both given to children with Juvenile Rheumatoid Arthritis (JRA) may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.

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Key information

Conditions

Juvenile Rheumatoid Arthritis Arthritis Arthritis, Juvenile Autoimmune Diseases Connective Tissue Diseases Immune System Diseases Joint Diseases Musculoskeletal Diseases Rheumatic Diseases Skin and Connective Tissue Diseases

Age range

3 year–15 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

University of Missouri Hospitals and clinics

Columbia, Missouri, 65203, United States

About this study

Supplementation With 2000 IU Vitamin D, 1 gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid Arthritis may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Juvenile Rheumatoid arthritis

Exclusion criteria

  • Steroid use

Treatment and study plan

Cholecalciferol

Dietary Supplement

2000IU Cholecalciferol P.O. Q.D.

Calcium

Dietary Supplement

1 gm calcium as calcium carbonate

Calcium and cholecalciferol

Dietary Supplement

2000IU cholecalciferol and 1 gm calcium P.O. Q.D. for 6 months

Placebo

Drug

Placebo

Primary outcomes

  1. Percent true calcium absorption

    Time frame: After 6 months of treatment

Secondary outcomes

  1. Bone Mineralization by Dual Energy x-ray absorption

    Time frame: After 6 months treatment plus 3 month washout

Sponsors and collaborators

Lead sponsor

University of Missouri-Columbia

Other

Registry information

Official study title

Effect of Supplementation With 2000 International Units (IU) Vitamin D, 1gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid Arthritis

Important dates

Study start
1995
Primary completion
2002
Study completion
2002
First posted
Dec 11, 2007
Registry last updated
Oct 10, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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