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NCT Number: NCT07320092

Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound

Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical positioning. The development of atelectasis has been associated with postoperative hypoxemia and other pulmonary complications.

Lung ultrasound (LUS) has emerged as a reliable, radiation-free bedside imaging modality for the detection and monitoring of atelectasis. LUS allows assessment of lung aeration through standardized ultrasound patterns and scoring systems, enabling dynamic evaluation in the perioperative period.

This is a prospective, observational cohort study designed to compare the incidence and severity of atelectasis in patients undergoing surgery in the supine position versus the prone position under general anesthesia. Adult patients undergoing elective surgical procedures will be enrolled. No experimental intervention will be applied, and all anesthetic and surgical management will follow routine clinical practice.

Lung ultrasound examinations will be performed at predefined time points after induction of anesthesia and before extubation. A standardized lung ultrasound protocol and scoring system will be used to assess lung aeration loss and detect the presence of atelectasis.

The primary outcome of the study is the difference in atelectasis detected by lung ultrasound between supine and prone surgical positions. The secondary outcome is the change in lung ultrasound scores over time.

This study aims to clarify the effects of supine and prone positions on perioperative atelectasis and to support the clinical use of lung ultrasound as a noninvasive monitoring tool in perioperative and anesthetic practice..

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine

Istanbul, 34320, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients aged 18 years or older.
  • Patients scheduled for elective surgery under general anesthesia.
  • Patients undergoing surgery in the supine or prone position.
  • Patients able to provide informed consent.

Exclusion criteria

  • Emergency surgical procedures.
  • Pre-existing severe pulmonary disease affecting lung ultrasound assessment.
  • Hemodynamic instability requiring urgent intervention.
  • Contraindications to lung ultrasound examination.

Treatment and study plan

Primary outcomes

  1. Difference in lung ultrasound-detected atelectasis between supine and prone surgical positions

    Time frame: Perioperative (After induction of general anesthesia and before extubation)

    Lung aeration will be evaluated using the Lung Ultrasound Score (LUS), a semiquantitative scoring system assessing aeration loss in 12 lung regions.

    In the supine position, lung ultrasound assessment will be performed along:

    the parasternal line (intercostal spaces 1-4 and 4-8), the anterior axillary line (intercostal spaces 1-6 and 6-12), and the posterior axillary line (intercostal spaces 1-6 and 6-12).

    In the prone position, lung ultrasound assessment will be performed along:

    the paravertebral line (intercostal spaces 1-6 and 6-12), the posterior axillary line (intercostal spaces 1-6 and 6-12), and the anterior axillary line (intercostal spaces 1-6 and 6-12). Each lung region will be scored from 0 to 3, resulting in a total LUS ranging from 0 to 36, where higher scores indicate greater loss of aeration and more severe atelectasis.

    Assessments will be performed after induction of general anesthesia and before extubation.

Sponsors and collaborators

Lead sponsor

Istanbul University - Cerrahpasa

Other

Registry information

Official study title

Comparison of the Incidence of Atelectasis Assessed by Lung Ultrasound in Patients Undergoing Surgery in Supine and Prone Positions

Acronym: LUS-ATELEC

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 6, 2026
Registry last updated
Jul 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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