Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07666334

Subtransverse Process Interligamentary Plane Block Versus Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block for Analgesia in Pediatric Thoracotomy

This study aims to compare ultrasound guided subtransverse process interligamentary plane block versus rhomboid intercostal block combined with sub-serratus plane block for postoperative analgesia in pediatric thoracotomy.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Subtransverse Process Interligamentary Plane Block Agnosia Analgesia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Pediatric Thoracotomy Perceptual Disorders Rhomboid Intercostal Block Signs and Symptoms Sub-Serratus Plane Block

Age range

6 year–12 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location status: Recruiting

Location contact

Lobna M AboAlnassr, MD

SUB_INVESTIGATOR

Mohamed A Lotfy, MD

SUB_INVESTIGATOR

Mohammed S Elsharkawy, MD

SUB_INVESTIGATOR

Naglaa K Mohamed, MD

SUB_INVESTIGATOR

Walaa A Elbialy, MSc

CONTACT

[email protected]

00201095519412

About this study

Post-thoracotomy pain is one of the most severe types of pain on the first day of the surgery. In pediatric patients, inadequate analgesia may lead to adverse circulatory and respiratory compromise.

The subtransverse process interligamentary (STIL) plane block is a recently introduced technique that offers a safer alternative by targeting thoracic nerves without entering the paravertebral space.

Recently, some studies have shown that the rhomboid intercostal block (RIB) and the RIB combined with the sub-serratus plane block (RISS) can provide good analgesia effects after video assisted thoracoscope.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pediatric patients between 6 to 12 years.
  • Both sexes.
  • American Society of Anesthesiologists (ASA) Physical Status I - II.
  • Scheduled for thoracic surgery with thoracotomy incision under general anesthesia.

Exclusion criteria

  • Parents who refused regional anesthesia.
  • Patients were presented with advanced kidney, cardiac or liver diseases.
  • Coagulation and bleeding disorders.
  • Patients presented with skin or soft tissue infection at the proposed site of needle Insertion.
  • Patients with cognitive impairment.

Treatment and study plan

Standard intravenous analgesia

Other

Patients will receive no block intervention and standard intravenous analgesia will be given.

Subtransverse process interligamentary plane block

Other

Patients will receive ipsilateral ultrasound-guided subtransverse process interligamentary (STIL) plane block with bupivacaine 0.25% (0.5 mL/kg) after induction of general anesthesia.

Rhomboid intercostal block (RIB) combined with sub-serratus plan block group

Other

Patients will receive ipsilateral ultrasound-guided rhomboid intercostal block (RIB) combined with sub-serratus plan block group with bupivacaine 0.25% (0.5mL/kg) after induction of general anesthesia.

Primary outcomes

  1. Time to first rescue analgesia

    Time frame: 24 hours postoperatively

    Time to the first rescue analgesia will be recorded from the end of surgery till first dose of morphine adminstrated.

Secondary outcomes

  1. Degree of pain

    Time frame: 24 hours postoperatively

    Each patient will be instructed about postoperative pain assessment with VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be assessed after surgery over 24 hours (30 minutes postoperative, 2, 4, 6, 12, 24 hours.

  2. Total Opioids consumption

    Time frame: 24 hours postoperatively

    Morphine 0.05 mg /kg IV will be given as rescue analgesia if VAS score ≥4, morphine dose will not exceed 0.3 mg/kg/day.

  3. Intraoperative fentanyl consumption

    Time frame: Intraoperatively

    Fentanyl 0.5 μg/kg will be administrated in the case of inadequate analgesia that defined as an un explained increase of heart rate (HR) and/or mean arterial blood pressure (MAP) more than 20% above the preoperative values after exclusion of other causes.

Study contacts

Contact information is provided by the study sponsor or research team.

Walaa A Elbialy, MSc

CONTACT

[email protected]

00201095519412

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Ultrasound- Guided Subtransverse Process Interligamentary Plane Block Versus Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block for Analgesia in Pediatric Thoracotomy: A Randomized Controlled Study

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Jun 24, 2026
Registry last updated
Jun 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.