Skip to main content
OpenTrials
Completed

NCT Number: NCT01744756

Subconjunctival Bevacizumab and Recurrent Pterygium

A study to research whether subconjunctival bevacizumab injection may potentially suppress neovascularization in pterygium, retarding and decreasing the size of recurrent pterygium.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Recurrent Pterygium Conjunctival Diseases Eye Diseases Pterygium

Age range

40 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Instituto de Olhos de Goiania

Goiânia, Goiás, 74110120, Brazil

About this study

  • Pacients with recurrent pterygium
  • Anti-VEGF therapy -Bevacizumab

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Recurrent pterygium

Exclusion criteria

  • Pregnant or lactating women
  • History of myocardial infarction
  • History of stroke

Treatment and study plan

Bevacizumab

Drug

One subconjunctival aplication of Bevacizumabe 0,5ml

Other names: Avastin

Primary outcomes

  1. Pterygium size after subconjunctival bevacizumab

    Time frame: 8 weeks

    -Size of recurrent pterygium (measured in mm) after injection

Secondary outcomes

  1. Number of Participants with Adverse Events as a Measure of Safety and Tolerability

    Time frame: 8 weeks

    -Number of patients with hyposphagma and irritative symptoms after subconjunctival injection

Sponsors and collaborators

Lead sponsor

Instituto de Olhos de Goiania

Other

Registry information

Official study title

Interventional Trial of Subconjunctival Bevacizumab in Recurrent Pterygium

Acronym: BRP

Important dates

Study start
2012
Primary completion
2012
Study completion
2012
First posted
Dec 7, 2012
Registry last updated
Dec 7, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.