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OpenTrials
Completed

NCT Number: NCT06408779

Study on Surgical Treatment Strategies for Moderate Ischemic Mitral Regurgitation

This study aimed to compare the efficacy of isolated coronary artery bypass grafting and coronary artery bypass grafting + mitral valve repair in moderate ischemic mitral regurgitation patients through a cohort and explore the potential risk factors of the clinical outcomes.

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Key information

Conditions

Mitral Valve Insufficiency Cardiovascular Diseases Coronary Artery Bypass Heart Diseases Heart Valve Diseases Mitral Valve Annuloplasty

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College

Beijing, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult coronary artery disease patients complicated with moderate ischemic mitral regurgitation.
  • undergoing coronary artery bypass grafting with or without mitral valve repair.

Exclusion criteria

  • patients under the age of 18 years,
  • patients complicated with more than moderate ischemic mitral regurgitation or undergoing mitral valve replacement,
  • patients complicated with primary mitral valve disease other than ischemic mitral regurgitation, such as rheumatic mitral regurgitation or mitral valve leaflet prolapse,
  • patients undergoing concomitant aortic valve procedure.

Treatment and study plan

Mitral valve repair

Procedure

coronary artery bypass grafting concomitant mitral valve repair

Primary outcomes

  1. major adverse cardiovascular and cerebrovascular events

    Time frame: 2years

    the composite of all-cause death, rehospitalization for heart failure, non-fatal myocardial infarction, non-fatal stroke or repeat mitral valve surgery.

Sponsors and collaborators

Lead sponsor

China National Center for Cardiovascular Diseases

Other Gov

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
May 10, 2024
Registry last updated
May 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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