Study of Probiotic Use After Childbirth in Relation to Emotional Well-Being

Inclusion criteria

• Able and willing to give written informed consent
• Expectant mothers with singleton infant or mothers who have recently given birth to a singleton infant
• At least 18 years of age
• At risk for postpartum depression as defined: a hx of depression and/or, a hx of postpartum depression and/or by a prenatal EPDS score ≥ 8

Exclusion criteria

• Has active substance abuse in the past 6 months or a history of opioid use disorder
• Has diabetes mellitus except for diet controlled gestational diabetes
• Has uncontrolled thyroid disease
• Has inflammatory gastrointestinal disease
• Has active suicidal ideation
• Has a history of psychosis
• Has a history of an autism spectrum disorder
• Plans to take other probiotics (other than study product) during study participation
• Plans to take systemic hormonal contraception during study participation (Note: intra-uterine device is allowed)
• Is receiving any systemically administered immunosuppressant medication on a chronic basis
• Has a clinically significant or uncontrolled concomitant illness or condition that would put the subject at risk or jeopardize the objectives of the study
• Has a contraindication, sensitivity, or known allergy to any ingredient of the study product
• Is considered, in the opinion of the Principal Investigator (PI), to likely be a poor attendee or unlikely for any reason to be able to comply with the study procedures