Skip to main content
OpenTrials
Enrolling by Invitation

NCT Number: NCT01223092

Study of Gene Associations and Infertility

The purpose of this this study is to use DNA screening strategies to identify genes and localize genomic regions that are differentially expressed in patients with infertility to further understand the genetic basis for reproductive competence.

Enrolling by Invitation

Interested in participating?

Request Info

Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Reproductive Medicine Associates of New Jersey

Basking Ridge, New Jersey, 07920, United States

About this study

Experimental strategies seek to discover small variants in DNA sequences, which are associated with certain infertility parameters. The alleles being analyzed in in vitro fertilization (IVF) population are sought to be associated with functional differences in the expression of the gene product that are then mechanistically linked to infertility.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all patients undergoing fertility care

Exclusion criteria

  • none

Treatment and study plan

Primary outcomes

  1. Number of retrieved oocytes

    Time frame: 1 month

Secondary outcomes

  1. Fertilization rate

    Time frame: 1 month

    Number of oocytes that are fertilized

  2. Number of available embryos

    Time frame: 1 month

    Number of embryos that are available for transfer on day 3 or day 5

  3. Pregnancy rates

    Time frame: 1 year

    Clinical pregnancy rates (detection of pregnancy hormone bHCG in blood) and delivery rates.

Sponsors and collaborators

Lead sponsor

Reproductive Medicine Associates of New Jersey

Other

Registry information

Official study title

Genes and Gene Polymorphisms Associated With Infertility: Utilization of DNA Characteristics to Better Understand Reproductive Competence

Important dates

Study start
2006
Primary completion
2025
Study completion
2026
First posted
Oct 18, 2010
Registry last updated
Feb 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.