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Enrolling by Invitation

NCT Number: NCT07020975

Virtual Reality for Anxiety Relief in Infertile Women

This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures. The clinical trial will involve 80 participants, aged 18 to 50, who are receiving treatment at a healthcare facility in the Turkish Republic of Northern Cyprus (TRNC). The primary objective is to evaluate the effectiveness of VR as an intervention for reducing anxiety in individuals undergoing assisted reproductive treatments.

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Key information

Age range

18 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Cyprus Aydin University

Girne Kepuveia, Keryneia, 99000, Cyprus

About this study

This doctoral study aims to evaluate the use of virtual reality (VR) as an innovative, non-invasive intervention for managing anxiety during embryo transfer in assisted reproductive technology (ART). A randomized clinical trial will be conducted with 80 participants, aged 18 to 50, undergoing fertility treatment at a healthcare facility in the Turkish Republic of Northern Cyprus (TRNC).

Participants will be randomly assigned to one of two groups: the intervention group (n=40), which will experience a VR session both before and after the embryo transfer, and the control group (n=40), which will receive standard care without VR. Anxiety levels will be assessed using the State-Trait Anxiety Inventory (STAI) at two time points-pre- and post-embryo transfer.

The primary objective of this study is to determine the effectiveness of VR in reducing procedural anxiety, a factor known to negatively affect patient experience and potentially influence treatment outcomes. The findings are expected to support the integration of patient-centered, technology-enhanced strategies in reproductive healthcare practices.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Volunteered to participate in the research,
  • 18-50 years old
  • No vision and hearing problems,
  • Not disoriented in time and place,
  • Primary infertile
  • Not having communication problem
  • Can read & write
  • No mental pathological disease

Exclusion criteria

  • Secondary infertility
  • Having experienced bleeding, miscarriage, etc. after embryo transfer,
  • Difficulty communicating,
  • Problems such as migraine, vertigo, dizziness,
  • Patients who wear prescription glasses and have vision problems without glasses
  • Refused to participate in the research
  • Patients with psychiatric pathology

Treatment and study plan

VR glasses

Device

VR Glasses is used to help people be in a virtual reality other than their real life. What we use this for; to get away infertile women from her stressfull environment to another virtual reality before their embryo transfer.

Primary outcomes

  1. Anxiety level of the women who went through embryo transfer.

    Time frame: 1 year

    This study aims to assess the anxiety levels of women who undergo a virtual reality (VR) experience before and after embryo transfer. The participants will be divided into two groups: those who receive relaxing Zen music and view natural landscapes through VR glasses, and those who do not. Anxiety levels will be objectively measured using the State-Trait Anxiety Inventory, both before and after the embryo transfer procedure.

Sponsors and collaborators

Lead sponsor

Cyprus Aydin University

Other

Registry information

Official study title

The Effect of Virtual Reality Application on Anxiety Before and After Embryo Transfer in Infertile Women

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 13, 2025
Registry last updated
Jun 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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