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Completed

NCT Number: NCT01030016

Study of Atenolol Influence on Blood Pressure During Resistance Exercise

The study was designed to investigate if atenolol is able to blunt blood pressure increase during resistance exercise in hypertensive subjects.

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Key information

Conditions

Blood Pressure Behavior Exercise Motor Activity

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

University of São Paulo

São Paulo, 05508030, Brazil

About this study

The study compared intra-arterial blood pressure responses during leg-extension resistance exercise performed to fatigue at 40, 80 and 100% of 1 RM in hypertensive patients receiving placebo (first) and atenolol (second) on a single blind manner.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • hypertension with blood pressure levels below 160/105 mmHg under placebo.
  • age between 30 and 60 years
  • nonobese

Exclusion criteria

  • target organ lesion
  • cardiovascular risk factor
  • cardiovascular disease
  • physically active

Treatment and study plan

Atenolol

Drug

25 mg/day, twice a day for 6 weeks

Other names: beta-blockers

Primary outcomes

  1. blood pressure during resistance exercise

    Time frame: 6 weeks

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Collaborators

  • Fundação de Amparo à Pesquisa do Estado de São Paulo

Registry information

Official study title

Blood Pressure Response During Resistance Exercise in Hypertensives: Influence of Beta-blockers

Important dates

Study start
2007
Primary completion
2009
Study completion
2009
First posted
Dec 10, 2009
Registry last updated
Dec 15, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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